Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1363661
Abstract: Although the pharmacological inhibition of cholesterol ester transport protein (CETP) has been proposed as a method of preventing and treating cardiovascular disease (CVD), the adverse effects of current inhibitors have cast doubt on the interaction… read more here.
Keywords: protein; mechanism; cholesterol ester; cetp ... See more keywords
Deficiency of neutral cholesterol ester hydrolase 1 (NCEH1) impairs endothelial function in diet-induced diabetic mice
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DOI: 10.1186/s12933-024-02239-6
Abstract: Neutral cholesterol ester hydrolase 1 (NCEH1) plays a critical role in the regulation of cholesterol ester metabolism. Deficiency of NCHE1 accelerated atherosclerotic lesion formation in mice. Nonetheless, the role of NCEH1 in endothelial dysfunction associated… read more here.
Keywords: mice; endothelial function; cholesterol ester;