Peroxisome Proliferator-Activated Receptor-γ Prevents Cholesterol Gallstone Formation in C57bl Mice by Regulating Bile Acid Synthesis and Enterohepatic Circulation
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/7475626
Abstract: To investigate the role of the peroxisome proliferator-activated receptor-γ (PPARγ) in the progression of cholesterol gallstone disease (CGD), C57bl/6J mice were randomized to the following groups (n=7/group): L (lithogenic diet, LGD), LM (LGD+pioglitazone), CM (chow… read more here.
Keywords: enterohepatic circulation; ppar; circulation; cholesterol gallstone ... See more keywords
Inhibition of Ceramide Decreased the Expression of ATP-Binding Cassette Transporter G5/8 mRNA in an Animal Model of Cholesterol Gallstone
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases"
DOI: 10.1159/000465517
Abstract: Background: The increased risk of gallstone has been reported in patients with ATP-binding cassette (ABC) transporter polymorphism. The half-transporters ABCG5 and ABCG8 mediate the efflux of cholesterol in hepatocytes and the intestine. We investigated whether… read more here.
Keywords: myriocin; group; cholesterol; cholesterol gallstone ... See more keywords
The long non-coding RNA MEG3 plays critical roles in the pathogenesis of cholesterol gallstone
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.10803
Abstract: Background Cholesterol gallstone (CG) is the most common gallstone disease, which is induced by biliary cholesterol supersaturation. The purpose of this study is to investigate the pathogenesis of CG. Methods Sixteen mice were equally and… read more here.
Keywords: meg3; network; group; cholesterol ... See more keywords