Flaxseed-derived peptides ameliorate hepatic cholesterol metabolism in Sprague-Dawley rats fed a high-cholesterol and high-fat diet.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11888
Abstract: BACKGROUND Plant peptides have been reported to have cholesterol-lowering activities. Previous research has found that ≤1k Da flaxseed peptide (FP5 ) reduces cholesterol absorption and synthesis in vitro. In this research, we investigate the cholesterol-lowering… read more here.
Keywords: high cholesterol; cholesterol; hepatic cholesterol; fed high ... See more keywords
Hepatic transcript signatures predict atherosclerotic lesion burden prior to a 2-year high cholesterol, high fat diet challenge
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271514
Abstract: The purpose of this study was to identify molecular mechanisms by which the liver influences total lesion burden in a nonhuman primate model (NHP) of cardiovascular disease with acute and chronic feeding of a high… read more here.
Keywords: lesion burden; cholesterol high; lesion; high fat ... See more keywords