Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.5271
Abstract: Importance Protein-truncating variants (PTVs) in apolipoprotein B (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9) are associated with significantly lower low-density lipoprotein (LDL) cholesterol concentrations. The association of these PTVs with coronary heart disease (CHD)… read more here.
Keywords: apob pcsk9; ldl cholesterol; cholesterol level; risk ... See more keywords
Effect of total cholesterol level variabilities on cerebrovascular disease.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202201_27882
Abstract: OBJECTIVE Hyperlipidemia is a risk factor of cerebrovascular disease (CVD). However, the relationship between CVD and cholesterol variability is less clear. This study assesses the relationship between cholesterol change and CVD risk. PATIENTS AND METHODS… read more here.
Keywords: cholesterol; ahr1 ahr2; cholesterol level; occlusion stenosis ... See more keywords
Inverse Association between Statin Use and Cancer Mortality Relates to Cholesterol Level
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14122920
Abstract: Simple Summary We observed that the inverse association between statin use and cancer mortality is limited to men with a reduction in cholesterol after the commencement of statins. These findings demonstrate that the observed inverse… read more here.
Keywords: cancer mortality; cholesterol level; statin use; mortality ... See more keywords