Assessment of Sex Disparities in Nonacceptance of Statin Therapy and Low-Density Lipoprotein Cholesterol Levels Among Patients at High Cardiovascular Risk
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.1047
Abstract: Key Points Question How are sex disparities in nonacceptance of statin therapy associated with control of low-density lipoprotein (LDL) cholesterol levels? Findings In this cohort study of 24 212 adults at high cardiovascular risk, patients who… read more here.
Keywords: sex disparities; therapy; statin therapy; cardiovascular risk ... See more keywords
Smoking is a cause of amyotrophic lateral sclerosis. High low‐density lipoprotein cholesterol levels? Unsure
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25468
Abstract: Identifying mechanisms of neurodegenerative disease causation has long seemed to be beyond the reach of traditional epidemiological tools. Elucidating a plausible mechanism for initiation of amyotrophic lateral sclerosis (ALS) has appeared particularly elusive. The impression… read more here.
Keywords: cholesterol levels; ldl; cholesterol; amyotrophic lateral ... See more keywords
The relationship between directly measured statin adherence, self-reported adherence measures and cholesterol levels in patients with coronary heart disease.
Sign Up to like & getrecommendations! Published in 2021 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2021.09.020
Abstract: BACKGROUND AND AIMS We aimed to determine the relationship between statin adherence measured directly, and by self-report measures and serum cholesterol levels. METHODS Patients prescribed atorvastatin (N = 373) participated in a cross-sectional study 2-36 months after… read more here.
Keywords: statin adherence; self reported; cholesterol levels; adherence ... See more keywords
Rev‐erb regulation of cholesterologenesis
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.02.006
Abstract: ABSTRACT REV‐ERB&agr; and REV‐ERB&bgr; are heme regulated nuclear receptors that are known to regulate metabolic pathways. We previously demonstrated that treatment of mice with synthetic REV‐ERB agonists suppressed plasma cholesterol levels and the hepatic levels… read more here.
Keywords: rev erb; expression; rev; cholesterol levels ... See more keywords
Dapagliflozin in patients with type II diabetes mellitus, with and without elevated triglyceride and reduced high-density lipoprotein cholesterol levels.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.01.018
Abstract: BACKGROUND Dapagliflozin is a selective sodium-glucose cotransporter 2 inhibitor that improves glycemic control in patients with type II diabetes mellitus (T2DM) by reducing renal glucose reabsorption. OBJECTIVE The aim was to evaluate the lipid effects… read more here.
Keywords: patients type; cholesterol levels; elevated triglyceride; density lipoprotein ... See more keywords
Cholesterol Levels in Patients with Chronic Lymphocytic Leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the National Medical Association"
DOI: 10.1016/j.jnma.2016.11.006
Abstract: Low cholesterol levels may be accompanied by solid tumors or hematological malignancies such as multiple myeloma. Decreased cholesterol levels have been reported in some experimental studies about chronic lymphocytic leukemia (CLL). It may be associated… read more here.
Keywords: control group; lymphocytic leukemia; cholesterol levels; cholesterol ... See more keywords
Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105222
Abstract: AIMS The estrogen-inducible protein Heat Shock Protein 27 (HSP27) as well as anti-HSP27 antibodies are elevated in healthy subjects compared to cardiovascular disease patients. Vaccination of ApoE-/- mice with recombinant HSP25 (rHSP25, the murine ortholog),… read more here.
Keywords: cholesterol levels; hsp27; pcsk9; post ... See more keywords
Consortia of bioactives in supercritical carbon dioxide extracts of mustard and small cardamom seeds lower serum cholesterol levels in rats: new leads for hypocholesterolaemic supplements from spices
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nutritional Science"
DOI: 10.1017/jns.2019.28
Abstract: Abstract Melatonin-rich and 1,8-cineole-rich extracts have been successfully obtained from yellow mustard (YM) and small cardamom (SC) seeds, respectively, employing green technology of supercritical CO2 (SC-CO2) extraction. Chemical profiling confirmed the presence of melatonin and… read more here.
Keywords: seed; cholesterol levels; small cardamom; mustard small ... See more keywords
Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48972-x
Abstract: While evidence supporting the notion that exposures to heavy ion radiation increase the risk for cancer and other disease development is accumulating, the underlying biological mechanisms remain poorly understood. To identify novel phenotypes that persist… read more here.
Keywords: cholesterol levels; cholesterol; cholesterol biosynthesis; lung tissue ... See more keywords
Activation of 5-HT2 Receptors Reduces Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-49987-0
Abstract: Coronary artery disease (CAD) is a progressive cardiovascular syndrome characterized by cholesterol-induced focal arterial lesions that impair oxygen delivery to the heart. As both innate and adaptive immune cells play critical roles in the formation… read more here.
Keywords: vascular tissue; cholesterol levels; cholesterol; high fat ... See more keywords
Tauroursodeoxycholic acid (TUDCA) counters osteoarthritis by regulating intracellular cholesterol levels and membrane fluidity of degenerated chondrocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00426b
Abstract: Cholesterol and lipid metabolism are associated with osteoarthritis (OA) in human cartilage. High cholesterol levels in OA chondrocytes leads to decreased membrane fluidity and blocks the signaling cascade associated with the expression of chondrogenic genes.… read more here.
Keywords: cholesterol levels; tudca; membrane fluidity; cholesterol ... See more keywords