Retardation of Antigen Release from DNA Hydrogel Using Cholesterol‐Modified DNA for Increased Antigen‐Specific Immune Response
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700355
Abstract: Our previous study indicates that cationization of an antigen is effective for sustained release of both immunostimulatory DNA containing unmethylated cytosine-phosphate-guanine (CpG) dinucleotides, or CpG DNA, and antigen from a DNA hydrogel. Another approach to… read more here.
Keywords: cholesterol modified; dna; dna hydrogel; antigen ... See more keywords
Cholesterol-Modified Oligonucleotides as Internal Reaction Controls during DNA-Encoded Chemical Library Synthesis.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00045
Abstract: We report two cholesterol-modified oligonucleotides for use as internal controls for on-DNA reactions during the pooled stages of a DNA-encoded chemical library (DECL) synthesis. As these cholesterol-tagged oligonucleotides are chromatographically separable from normal DECL intermediates,… read more here.
Keywords: controls dna; cholesterol modified; modified oligonucleotides; cholesterol ... See more keywords