Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?
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DOI: 10.3390/ijms20163858
Abstract: Liver X Receptors (LXR) alpha and beta are two members of nuclear receptor superfamily documented as endogenous cholesterol sensors. Following conversion of cholesterol in oxysterol, both LXR isoforms detect intracellular concentrations and act as transcription… read more here.
Keywords: cholesterol oxysterol; brain cholesterol; cholesterol; liver receptors ... See more keywords