Lingguizhugan Decoction Protects against High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease by Alleviating Oxidative Stress and Activating Cholesterol Secretion
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DOI: 10.1155/2017/2790864
Abstract: Background Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of liver transplantation. Lingguizhugan decoction (LGZG), a classical Chinese herbal formula, has beneficial effects on NAFLD animal models. Our study examined the impact of… read more here.
Keywords: nonalcoholic fatty; cholesterol secretion; secretion; oxidative stress ... See more keywords
miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway
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DOI: 10.7150/ijbs.65485
Abstract: miRNA-223 has been previously reported to play an essential role in hepatic cholesterol homeostasis. However, its role in regulation of biliary cholesterol secretion and gallstone formation remains unknown. Hence, mice with conventional knockout (KO), hepatocyte-specific… read more here.
Keywords: cholesterol secretion; mirna 223; cholesterol; gallstone formation ... See more keywords