Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13157
Abstract: Apolipoprotein M (ApoM) exhibits various anti‐atherosclerotic functions as a component of high‐density lipoprotein (HDL) particles. Scavenger receptor class B type I (SR‐BI) is a classic HDL receptor that mediates selective cholesterol uptake and enhances the… read more here.
Keywords: hdl; mouse macrophages; cholesterol uptake; apom ... See more keywords
Association of ANGPTL3 polymorphisms with high-density lipoprotein cholesterol uptake capacity in patients with cardiovascular disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.23980
Abstract: INTRODUCTION Previous studies have shown the importance of angiopoietin-like 3 (ANGPTL3) as a modulator of lipid profiles. Cholesterol uptake capacity (CUC) is one means for assessing high-density lipoprotein (HDL) functionality. This study for the first… read more here.
Keywords: uptake capacity; high density; density lipoprotein; disease ... See more keywords
Cholesterol uptake or trafficking, steroid biosynthesis, and gonadotropin responsiveness are defective in young poor responders.
Sign Up to like & getrecommendations! Published in 2022 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2022.01.024
Abstract: OBJECTIVE To investigate whether poor ovarian response in young patients undergoing in vitro fertilization simply involves lesser follicle growth due to diminished ovarian reserve or whether there are intrinsic perturbations in the ovary. DESIGN A translational… read more here.
Keywords: cholesterol uptake; follicle; poor responders; hormone ... See more keywords
Xanthohumol suppresses NPC1L1 gene expression through down-regulation of HNF-4α and inhibits cholesterol uptake in Caco-2 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05221
Abstract: Xanthohumol (Xan) is a prenylated chalcone mainly found in hops, it has been demonstrated to function against hypercholesterolemia, hyperlipidemia, and atherosclerosis. In this study, we focused on the hypocholesterolemic effect of Xan on cholesterol uptake… read more here.
Keywords: caco cells; xan; hnf; expression ... See more keywords
Neuropeptide Y regulates cholesterol uptake and efflux in macrophages and promotes foam cell formation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17561
Abstract: The dysregulation of lipid metabolic pathways (cholesterol uptake and efflux) in macrophages results in the formation of lipid‐dense macrophages, named foam cells, that participate in plaque formation. NPY binding to NPY receptors in macrophages can… read more here.
Keywords: cholesterol uptake; uptake efflux; efflux macrophages; formation ... See more keywords
Inhibitory Effect of Isoliquiritigenin in Niemann-Pick C1-Like 1-Mediated Cholesterol Uptake
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27217494
Abstract: Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure extracted from the natural herb Glycyrrhiza glabra. Its anti-inflammatory, antibacterial, antioxidant, and anticancer activities have been extensively studied. Moreover, ISL also possess hypolipidemic and atherosclerosis-reducing effects.… read more here.
Keywords: effect; isoliquiritigenin; cholesterol uptake; pick like ... See more keywords