Gestational cholestyramine treatment protects adult offspring of ApoE‐deficient mice against maternal‐hypercholesterolemia‐induced atherosclerosis
Sign Up to like & getrecommendations! Published in 2024 at "Acta Physiologica"
DOI: 10.1111/apha.14133
Abstract: Perinatal hypercholesterolemia exacerbates the development of atherosclerotic plaques in adult offspring. Here, we aimed to study the effect of maternal treatment with cholestyramine, a lipid‐lowering drug, on atherosclerosis development in adult offspring of hypercholesterolemic ApoE‐deficient… read more here.
Keywords: mice; adult offspring; treatment; cholestyramine ... See more keywords
Cholestyramine alleviates bone and muscle loss in irritable bowel syndrome via regulating bile acid metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Cell Proliferation"
DOI: 10.1111/cpr.13638
Abstract: Irritable bowel syndrome (IBS) is a widespread gastrointestinal disorder known for its multifaceted pathogenesis and varied extraintestinal manifestations, yet its implications for bone and muscle health are underexplored. Recent studies suggest a link between IBS… read more here.
Keywords: bone muscle; cholestyramine; muscle; muscle loss ... See more keywords