Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
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DOI: 10.1371/journal.pone.0171080
Abstract: Intersections in hepatic methyl group metabolism pathways highlights potential competition or compensation of methyl donors. The objective of this experiment was to examine the expression of genes related to methyl group transfer and lipid metabolism… read more here.
Keywords: methyl; choline methionine; metabolism; methionine ... See more keywords
The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030471
Abstract: The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent phospholipase… read more here.
Keywords: methionine metabolism; pnpla7; methionine; choline methionine ... See more keywords
Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes
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DOI: 10.3390/ijms20235937
Abstract: Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis. Dysregulated methionine cycle is reported in animal models of WD, though not verified in humans.… read more here.
Keywords: choline methionine; metabolism; methionine; methionine aromatic ... See more keywords