The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation.
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DOI: 10.1073/pnas.2209435120
Abstract: Aberrantly upregulated choline phospholipid metabolism is a novel emerging hallmark of cancer, and choline kinase α (CHKα), a key enzyme for phosphatidylcholine production, is overexpressed in many types of human cancer through undefined mechanisms. Here,… read more here.
Keywords: choline phospholipid; metabolism; phospholipid metabolism; glycolytic enzyme ... See more keywords