Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22700
Abstract: Down syndrome (DS), trisomy 21, is marked by intellectual disability and a premature aging profile including degeneration of the basal forebrain cholinergic neuron (BFCN) projection system, similar to Alzheimer's disease (AD). Although data indicate that… read more here.
Keywords: cholinergic neuron; choline; choline supplementation; maternal choline ... See more keywords
Choline diet improves serum lipid parameters and alters egg composition in breeder ducks
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.798
Abstract: Abstract Background Choline is an important nutrient, playing key roles in numerous metabolic pathways relevant to animal health. Objectives The objective of this study was to evaluate the effect of dietary choline on the lipid… read more here.
Keywords: choline supplementation; choline; breeder ducks; lipid parameters ... See more keywords
Maternal Choline Supplementation Mitigates Alcohol-Induced Fetal Cranio-Facial Abnormalities Detected Using an Ultrasonographic Examination in A Sheep Model.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2019.05.001
Abstract: Early detection of prenatal alcohol exposure is critical for designing and testing effectiveness of interventional therapeutics. Choline supplementation during and after prenatal alcohol exposure has shown promising benefits in improving outcomes in rodent models and… read more here.
Keywords: choline; choline supplementation; maternal choline; binge ... See more keywords
Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies
Sign Up to like & getrecommendations! Published in 2018 at "Alcoholism: Clinical and Experimental Research"
DOI: 10.1111/acer.13817
Abstract: Prenatal alcohol exposure results in cognitive, behavioral, and neurological deficits in offspring. There is an urgent need for safe and effective treatments to overcome these effects. Maternal choline supplementation has been identified as a potential… read more here.
Keywords: alcohol exposure; preclinical studies; choline supplementation; exposure ... See more keywords
Maternal choline supplementation during pregnancy to promote mental health in offspring.
Sign Up to like & getrecommendations! Published in 2023 at "Early intervention in psychiatry"
DOI: 10.1111/eip.13426
Abstract: AIM There is increasing interest in the role of choline in brain development, including its possible role in promoting mental health and preventing mental illness. Choline is an essential micronutrient in fetal brain maturation. In… read more here.
Keywords: choline supplementation; choline; maternal choline; mental health ... See more keywords
Dietary choline supplementation regulated lipid profiles of egg yolk, blood, and liver and improved hepatic redox status in laying hens.
Sign Up to like & getrecommendations! Published in 2019 at "Poultry science"
DOI: 10.3382/ps/pez139
Abstract: Five hundred and forty 19-wk-old HyLine Brown laying hens were randomly distributed to 6 dietary treatments and fed 1of 6 corn-soybean meal-based diets added into choline with 0, 425, 850, 1,700, 3,400, and 6,800 mg/kg to… read more here.
Keywords: choline; dietary choline; choline supplementation; laying hens ... See more keywords
Prenatal and Postnatal Choline Supplementation in Fetal Alcohol Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030688
Abstract: Fetal alcohol spectrum disorder (FASD) is common and represents a significant public health burden, yet very few interventions have been tested in FASD. Cognitive deficits are core features of FASD, ranging from broad intellectual impairment… read more here.
Keywords: choline supplementation; choline; alcohol spectrum; fetal alcohol ... See more keywords
Choline Supplementation Does Not Promote Atherosclerosis in CETP-Expressing Male Apolipoprotein E Knockout Mice
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14081651
Abstract: Dietary trimethylamines, such as choline, metabolized by intestinal microbiota to trimethylamine are absorbed by the gut and oxidized to trimethylamine N-oxide (TMAO). The objective of this study was to determine the effect of choline supplementation… read more here.
Keywords: choline supplementation; promote atherosclerosis; choline; mice expressing ... See more keywords
Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14102004
Abstract: Prenatal ethanol exposure (PNEE) is a leading cause of neurodevelopmental impairments, yet treatments for individuals with PNEE are limited. Importantly, postnatal supplementation with the essential nutrient choline can attenuate some adverse effects of PNEE on… read more here.
Keywords: choline supplementation; supplementation; ethanol exposure; prenatal ethanol ... See more keywords
Choline Supplementation Modifies the Effects of Developmental Alcohol Exposure on Immune Responses in Adult Rats
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14142868
Abstract: Prenatal alcohol exposure can disrupt the development of numerous systems, including the immune system. Indeed, alterations in cytokine levels may contribute to the neuropathological, behavioral, and cognitive problems, and other adverse outcomes observed in individuals… read more here.
Keywords: choline supplementation; adult rats; alcohol; alcohol exposure ... See more keywords