Longitudinal Alzheimer's Degeneration Reflects the Spatial Topography of Cholinergic Basal Forebrain Projections.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.06.001
Abstract: The cholinergic neurons of the basal forebrain (BF) provide virtually all of the brain's cortical and amygdalar cholinergic input. They are particularly vulnerable to neuropathology in early Alzheimer's disease (AD) and may trigger the emergence… read more here.
Keywords: topography; basal forebrain; cortico amygdalar; degeneration ... See more keywords
Quantification of brain cholinergic denervation in dementia with Lewy bodies using PET imaging with [18F]-FEOBV
Sign Up to like & getrecommendations! Published in 2018 at "Molecular psychiatry"
DOI: 10.1038/s41380-018-0130-5
Abstract: [18F]-fluoroethoxybenzovesamicol ([18F]-FEOBV) is a vesamicol analogue selectively binding the vesicular acetylcholine transporter (VAChT), a protein expressed uniquely by cholinergic neurons1. Non-invasive and short duration PET imaging acquisition protocols allowing accurate quantification of VAChT are preferred… read more here.
Keywords: pet imaging; brain cholinergic; quantification; quantification brain ... See more keywords