Articles with "cholinergic dysfunction" as a keyword



7, 8-dihydroxyflavone Ameliorates Cholinergic Dysfunction, Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Vascular Dementia

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Published in 2024 at "Neurochemical Research"

DOI: 10.1007/s11064-023-04090-9

Abstract: Vascular dementia (VD) is a degenerative cerebrovascular disorder associated with progressive cognitive decline. Previous reports have shown that 7,8-dihydroxyflavone (7,8-DHF), a well-known TrkB agonist, effectively ameliorates cognitive deficits in several disease models. Therefore, this study… read more here.

Keywords: vascular dementia; cholinergic dysfunction; oxidative stress; model ... See more keywords

Visual hallucinations in Parkinson’s disease: spotlight on central cholinergic dysfunction

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Published in 2024 at "Brain"

DOI: 10.1093/brain/awae289

Abstract: Abstract Visual hallucinations are a common non-motor feature of Parkinson’s disease and have been associated with accelerated cognitive decline, increased mortality and early institutionalization. Despite their prevalence and negative impact on patient outcomes, the repertoire… read more here.

Keywords: cholinergic dysfunction; central cholinergic; parkinson disease; visual hallucinations ... See more keywords

Neuro-protective Effect of Acetyl-11-keto-β-boswellic Acid in a Rat Model of Scopolamine-induced Cholinergic Dysfunction.

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Published in 2024 at "Current pharmaceutical design"

DOI: 10.2174/0113816128269289231226115446

Abstract: BACKGROUND Acetyl-11-keto-β-boswellic acid (AKBA) is a major component of the oleo-gum resin of B. serrata with multiple pharmacological activities. The objective of this study was to explore the underlying mechanisms of neuroprotective potential of AKBA… read more here.

Keywords: scopolamine; acetyl keto; cholinergic dysfunction; dysfunction ... See more keywords

A Potential Role of Cholinergic Dysfunction on Impaired Colon Motility in Experimental Intestinal Chagas Disease

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Published in 2022 at "Journal of Neurogastroenterology and Motility"

DOI: 10.5056/jnm21074

Abstract: Background/Aims Chagasic megacolon is caused by Trypanosoma cruzi, which promotes in several cases, irreversible segmental colonic dilation. This alteration is the major anatomic-clinical disorder, characterized by the enteric nervous system and muscle wall structural damage.… read more here.

Keywords: role cholinergic; cholinergic dysfunction; motility; potential role ... See more keywords