Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder
Sign Up to like & getrecommendations! Published in 2020 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.12.013
Abstract: Background Generalized anxiety disorder is associated with hyperactivity in the amygdala-prefrontal networks, and normalization of this aberrant function is thought to be critical for successful treatment. Preclinical evidence implicates cholinergic neurotransmission in the function of… read more here.
Keywords: cholinergic modulation; anxiety; disorder; generalized anxiety ... See more keywords
Cholinergic Modulation Promotes Attentional Modulation in Primary Visual Cortex- A Modeling Study
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-56608-3
Abstract: Attention greatly influences sensory neural processing by enhancing firing rates of neurons that represent the attended stimuli and by modulating their tuning properties. The cholinergic system is believed to partly mediate the attention contingent improvement… read more here.
Keywords: modulation; cholinergic modulation; attention; primary visual ... See more keywords
Cholinergic modulation of the hippocampal region and memory function
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14052
Abstract: Acetylcholine (ACh) plays an important role in memory function and has been implicated in aging‐related dementia, in which the impairment of hippocampus‐dependent learning strongly manifests. Cholinergic neurons densely innervate the hippocampus, mediating the formation of… read more here.
Keywords: cholinergic modulation; memory function; memory; modulation hippocampal ... See more keywords
Ovariectomy reduces cholinergic modulation of excitatory synaptic transmission in the rat entorhinal cortex
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271131
Abstract: Estrogens are thought to contribute to cognitive function in part by promoting the function of basal forebrain cholinergic neurons that project to the hippocampus and cortical regions including the entorhinal cortex. Reductions in estrogens may… read more here.
Keywords: ovariectomy; entorhinal cortex; excitatory synaptic; cortex ... See more keywords
Cholinergic Modulation of Type 2 Immune Responses
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01873
Abstract: In recent years, the bidirectional relationship between the nervous and immune system has become increasingly clear, and its role in both homeostasis and inflammation has been well documented over the years. Since the introduction of… read more here.
Keywords: immune; cholinergic modulation; immune responses; type immune ... See more keywords
Temporal dynamics of cholinergic activity in the septo-hippocampal system
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.957441
Abstract: Cholinergic projection neurons in the medial septum and diagonal band of Broca are the major source of cholinergic modulation of hippocampal circuit functions that support neural coding of location and running speed. Changes in cholinergic… read more here.
Keywords: speed; temporal dynamics; running speed; activity ... See more keywords
A Computational Model of the Cholinergic Modulation of CA1 Pyramidal Cell Activity
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Computational Neuroscience"
DOI: 10.3389/fncom.2020.00075
Abstract: Dysfunction in cholinergic modulation has been linked to a variety of cognitive disorders including Alzheimer's disease. The important role of this neurotransmitter has been explored in a variety of experiments, yet many questions remain unanswered… read more here.
Keywords: model; cholinergic modulation; ca1 pyramidal; pyramidal cell ... See more keywords
Cholinergic Modulation of Neuroinflammation: Focus on α7 Nicotinic Receptor
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22094912
Abstract: All nervous system pathologies (e.g., neurodegenerative/demyelinating diseases and brain tumours) develop neuroinflammation, a beneficial process during pathological events, aimed at removing damaged cells, toxic agents, and/or pathogens. Unfortunately, excessive inflammation frequently occurs during nervous system… read more here.
Keywords: modulation neuroinflammation; cholinergic modulation; neuroinflammation; nicotinic receptor ... See more keywords
Cholinergic Modulation of Locomotor Circuits in Vertebrates
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810738
Abstract: Locomotion is a basic motor act essential for survival. Amongst other things, it allows animals to move in their environment to seek food, escape predators, or seek mates for reproduction. The neural mechanisms involved in… read more here.
Keywords: locomotion; modulation; cholinergic inputs; modulation locomotor ... See more keywords