Ciproxifan attenuates the memory impairment induced by lipopolysaccharide through modulation of cholinergic transmission in the mouse brain.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202203_28335
Abstract: OBJECTIVE We investigated the protective effect of ciproxifan on lipopolysaccharide (LPS)-induced memory impairment by altering the cholinergic system in a mouse model. MATERIALS AND METHODS Groups of mice were given ciproxifan (1 or 3 mg/kg,… read more here.
Keywords: memory impairment; brain; mouse; cholinergic transmission ... See more keywords
Corticofugal and Brainstem Functions Associated With Medial Olivocochlear Cholinergic Transmission
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.866161
Abstract: Cholinergic transmission is essential for survival and reproduction, as it is involved in several physiological responses. In the auditory system, both ascending and descending auditory pathways are modulated by cholinergic transmission, affecting the perception of… read more here.
Keywords: cholinergic transmission; transmission; medial olivocochlear; corticofugal brainstem ... See more keywords
Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation.
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DOI: 10.4155/fmc-2017-0039
Abstract: AIM Alzheimer pathogenesis has been associated with a network of processes working simultaneously and synergistically. Over time, much interest has been focused on cholinergic transmission and its mutual interconnections with other active players of the… read more here.
Keywords: cholinergic transmission; drug design; multitarget drug; design strategy ... See more keywords
Implication of cholinergic transmission in rat model of spinal cord injury: A potential therapeutic target
Sign Up to like & getrecommendations! Published in 2021 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v18i4.9
Abstract: Purpose: To assess the involvement of cholinergic transmission in the etiology of spinal cord injury (SCI) in a rat model. Methods: Male adult rats (Wistar) with body weight ranging from 200 to 250 g were… read more here.
Keywords: sci; rat model; cholinergic transmission; cord injury ... See more keywords