GRP75 as a functional element of cholix transcytosis
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DOI: 10.1080/21688370.2022.2039003
Abstract: ABSTRACT Cholix (Chx) is secreted by non-pandemic strains of Vibrio cholerae in the intestinal lumen. For this exotoxin to induce cell death in non-polarized cells in the intestinal lamina propria, it must traverse the epithelium… read more here.
Keywords: cholix; transcytosis pathway; lamina propria; transcytosis ... See more keywords
Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway
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DOI: 10.3390/toxins16090380
Abstract: Vibrio cholerae is an important foodborne pathogen. Cholix cytotoxin (Cholix), produced by V. cholerae, is a novel eukaryotic elongation factor 2 (eEF2) adenosine diphosphate ribosyltransferase that causes host cell death by inhibiting protein synthesis. However,… read more here.
Keywords: induced cell; cholix; cell death; cholix induced ... See more keywords