Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
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DOI: 10.3389/fphar.2022.791376
Abstract: Objective: Osteoarthritis (OA) is a common disease with a complex pathology including mechanical load, inflammation, and metabolic factors. Chondrocyte ferroptosis contributes to OA progression. Because iron deposition is a major pathological event in ferroptosis, deferoxamine… read more here.
Keywords: chondrocyte ferroptosis; ferroptosis; dfo; collagen expression ... See more keywords