The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation
Sign Up to like & getrecommendations! Published in 2017 at "Bone Reports"
DOI: 10.1016/j.bonr.2017.08.002
Abstract: Chondrocyte hypertrophy makes important contributions to bone development and growth. We have investigated a number of novel cartilage genes identified in a recent transcriptomic study to determine whether they are differentially expressed between different zones… read more here.
Keywords: medium; chondrocyte hypertrophy; differentiation; atpase ... See more keywords
Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.12.004
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Osteoarthritis (OA), characterized by joint pain and cartilage degradation, is the most common form of joint disease worldwide but with no satisfactory therapy available. The ethanol extract of Agkistrodon acutus (EAA) has been… read more here.
Keywords: apoptosis; chondrocyte hypertrophy; hypertrophy apoptosis; cartilage degradation ... See more keywords
HDAC4 mutant represses chondrocyte hypertrophy by locating in the nucleus and attenuates disease progression of posttraumatic osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-021-04947-6
Abstract: Background The aim of this study was to evaluate whether histone deacetylase 4 S246/467/632A mutant (m-HDAC4) has enhanced function at histone deacetylase 4 (HDAC4) to attenuate cartilage degeneration in a rat model of osteoarthritis (OA). Methods… read more here.
Keywords: treated hdac4; hdac4 gfp; hdac4 group; hdac4 ... See more keywords