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   Articles with "chondrocyte hypertrophy" as a keyword



The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation

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recommendations! Published in 2017 at "Bone Reports"

DOI: 10.1016/j.bonr.2017.08.002

Abstract: Chondrocyte hypertrophy makes important contributions to bone development and growth. We have investigated a number of novel cartilage genes identified in a recent transcriptomic study to determine whether they are differentially expressed between different zones… read more here.

Keywords: medium; chondrocyte hypertrophy; differentiation; atpase ... See more keywords

Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis.

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recommendations! Published in 2019 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2018.12.004

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Osteoarthritis (OA), characterized by joint pain and cartilage degradation, is the most common form of joint disease worldwide but with no satisfactory therapy available. The ethanol extract of Agkistrodon acutus (EAA) has been… read more here.

Keywords: apoptosis; chondrocyte hypertrophy; hypertrophy apoptosis; cartilage degradation ... See more keywords

HDAC4 mutant represses chondrocyte hypertrophy by locating in the nucleus and attenuates disease progression of posttraumatic osteoarthritis

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recommendations! Published in 2022 at "BMC Musculoskeletal Disorders"

DOI: 10.1186/s12891-021-04947-6

Abstract: Background The aim of this study was to evaluate whether histone deacetylase 4 S246/467/632A mutant (m-HDAC4) has enhanced function at histone deacetylase 4 (HDAC4) to attenuate cartilage degeneration in a rat model of osteoarthritis (OA). Methods… read more here.

Keywords: treated hdac4; hdac4 gfp; hdac4 group; hdac4 ... See more keywords

Bibliometric analysis of research trends and emerging insights of osteoarthritis and chondrocyte hypertrophy

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recommendations! Published in 2025 at "Frontiers in Surgery"

DOI: 10.3389/fsurg.2025.1538339

Abstract: Background This study aims to systematically analyze the intersection of OA and chondrocyte hypertrophy using bibliometric methods, providing an quantitative and comprehensive overview of the current research status and emerging trends in this field. Methods… read more here.

Keywords: analysis; chondrocyte hypertrophy; research; chondrocyte ... See more keywords

Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of Osteoarthritis

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recommendations! Published in 2025 at "Bioengineering"

DOI: 10.3390/bioengineering12010077

Abstract: Osteoarthritis (OA) is a common joint disease characterized by pain and functional impairment, which severely impacts the quality of life of middle-aged and elderly individuals. During normal bone development, chondrocyte hypertrophy is a natural physiological… read more here.

Keywords: targeting chondrocyte; hypertrophy; treatment; chondrocyte hypertrophy ... See more keywords