Glucocorticoid caused lactic acid accumulation and damage in human chondrocytes via ROS-mediated inhibition of Monboxylate Transporter 4.
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DOI: 10.1016/j.bone.2021.116299
Abstract: Osteoarthritis (OA) is a common joint disease lacking effective treatments. Dexamethasone (Dex) is often used to relieve joint pain. However, the adverse effects of Dex on cartilage can't be ignored. This study aimed to investigate… read more here.
Keywords: lactic acid; chondrocytes via; level; human chondrocytes ... See more keywords