Extracellular matrix derived from chondrocytes promotes rapid expansion of human primary chondrocytes in vitro with reduced dedifferentiation.
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DOI: 10.1016/j.actbio.2018.12.006
Abstract: A significant expansion of autologous chondrocytes in vitro is required for cell-based cartilage repair. However, the in vitro expansion of chondrocytes under standard culture conditions inevitably leads to the dedifferentiation of chondrocytes and contributes to… read more here.
Keywords: expansion; microscopy; vitro expansion; chondrocytes vitro ... See more keywords
Platelet-Rich Plasma Does Not Inhibit Inflammation or Promote Regeneration in Human Osteoarthritic Chondrocytes In Vitro Despite Increased Proliferation.
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DOI: 10.1177/1947603520961162
Abstract: OBJECTIVE The aims of the study were to assess the anti-inflammatory properties of platelet-rich plasma (PRP) and investigate its regenerative potential in osteoarthritic (OA) human chondrocytes. We hypothesized that PRP can modulate the inflammatory response… read more here.
Keywords: chondrocytes cultured; platelet rich; inflammation; proliferation ... See more keywords