Protective effect of extractive and biotechnological chondroitin in insulin amyloid and advanced glycation end productâinduced toxicity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27153
Abstract: Glycosaminoglycans are extracellular matrix components related to several biological functions and diseases. Chondroitin sulfate is a sulphated glycosaminoglycan synthesized as part of proteoglycan molecules. They are frequently associated with amyloid deposits and possess an active… read more here.
Keywords: amyloid; chondroitin; end; toxicity ... See more keywords
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2018): Satellite Symposia Abstracts
Sign Up to like & getrecommendations! Published in 2018 at "Osteoporosis International"
DOI: 10.1007/s00198-018-4458-0
Abstract: Osteoarthritis (OA) is a progressive joint disease, that occurs frequently in the aging population and is a major cause of disability worldwide. Both glucosamine and chondroitin are biologically active molecules that are substrates for proteoglycan… read more here.
Keywords: congress osteoporosis; chondroitin; evidence; world congress ... See more keywords
Inappropriate claims from non-equivalent medications in osteoarthritis: a position paper endorsed by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
Sign Up to like & getrecommendations! Published in 2017 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-017-0861-1
Abstract: Osteoarthritis (OA) is a progressive joint disease, that occurs frequently in the aging population and is a major cause of disability worldwide. Both glucosamine and chondroitin are biologically active molecules that are substrates for proteoglycan,… read more here.
Keywords: chondroitin; evidence; glucosamine; society clinical ... See more keywords
Preparation of low-molecular-weight chondroitin sulfates by complex enzyme hydrolysis and their antioxidant activities.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116302
Abstract: Chondroitin sulfate (CS) has attracted widespread attention because of its numerous pharmacological activities. Low-molecular-weight chondroitin sulfates (LMWCSs) derived from the degradation of CS are reported to have better biological properties than whole CS. In this… read more here.
Keywords: low molecular; antioxidant activities; chondroitin; molecular weight ... See more keywords
Molecular characterization of CHST11 and its potential role in nacre formation in pearl oyster Pinctada fucata martensii
Sign Up to like & getrecommendations! Published in 2017 at "Electronic Journal of Biotechnology"
DOI: 10.1016/j.ejbt.2017.06.002
Abstract: Background : C4ST-1 catalyses the transfer of sulfate groups in the sulfonation of chondroitin during chondroitin sulfate synthesis. Chondroitin sulfate consists of numerous copies of negatively charged sulfonic acid groups that participate in the nucleation… read more here.
Keywords: pmchst11a pmchst11b; mso; chondroitin; formation ... See more keywords
Enhancing fructosylated chondroitin production in Escherichia coli K4 by balancing the UDP-precursors.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2018.04.006
Abstract: Microbial production of chondroitin and chondroitin-like polysaccharides from renewable feedstock is a promising and sustainable alternative to extraction from animal tissues. In this study, we attempted to improve production of fructosylated chondroitin in Escherichia coli… read more here.
Keywords: production; escherichia coli; chondroitin; coli balancing ... See more keywords
Possible role of chondroitin sulphate and glucosamine for primary prevention of colorectal cancer. Results from the MCC-Spain study
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20349-6
Abstract: A safe and effective colorectal cancer (CRC) chemoprevention agent remains to be discovered. We aim to evaluate the association between the use of glucosamine and/or chondroitin sulphate and risk of colorectal cancer (CRC) in the… read more here.
Keywords: use; chondroitin; colorectal cancer; study ... See more keywords
Production and purification of higher molecular weight chondroitin by metabolically engineered Escherichia coli K4 strains
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DOI: 10.1038/s41598-020-70027-9
Abstract: The capsular polysaccharide obtained from Escherichia coli K4 is a glycosaminoglycan-like molecule, similar to chondroitin sulphate, that has established applications in the biomedical field. Recent efforts focused on the development of strategies to increase K4… read more here.
Keywords: higher molecular; escherichia coli; chondroitin; molecular weight ... See more keywords
Structural elucidation of fucosylated chondroitin sulfates from sea cucumber using FTICR-MS/MS
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Mass Spectrometry"
DOI: 10.1177/1469066717731900
Abstract: Fucosylated chondroitin sulfates are complex polysaccharides extracted from sea cucumber. They have been extensively studied for their anticoagulant properties and have been implicated in other biological activities. While nuclear magnetic resonance spectroscopy has been used… read more here.
Keywords: chondroitin; chondroitin sulfates; mass spectrometry; fucosylated chondroitin ... See more keywords
Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-018-0871-5
Abstract: ObjectiveTo assess the symptomatic effectiveness and safety of oral symptomatic slow-acting drugs (SYSADOAs) on the treatment of knee and/or hip osteoarthritis, such as chondroitin, glucosamine, and combination treatment with chondroitin plus glucosamine.MethodsWe searched electronic database… read more here.
Keywords: effectiveness safety; chondroitin; treatment; glucosamine ... See more keywords
N-glycolyl chondroitin synthesis using metabolically engineered E. coli
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DOI: 10.1186/s13568-020-01084-6
Abstract: N-glycolyl chondroitin (Gc-CN) is a metabolite of N-glycolylneuraminic acid (Neu5Gc), a sialic acid that is commonly found in mammals, but not humans. Humans can incorporate exogenous Neu5Gc into their tissues from eating red meat. Neu5Gc… read more here.
Keywords: chondroitin; glycolyl chondroitin; chondroitin synthesis; metabolically engineered ... See more keywords