Physicochemical, antioxidant and biocompatible properties of chondroitin sulphate isolated from chicken keel bone for potential biomedical applications.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.12.015
Abstract: Chicken keel bone cartilage was explored for cheaper and sustainable source for isolation of chondroitin sulphate (CS) for its future use in tissue engineering and pharmaceutical industry. HPSEC analysis displayed two peaks of 100kDa for… read more here.
Keywords: chondroitin sulphate; chicken keel; keel bone; keel ... See more keywords
In-silico prediction of role of chitosan, chondroitin sulphate and agar in process of wound healing towards scaffold development
Sign Up to like & getrecommendations! Published in 2020 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2020.100406
Abstract: Abstract Natural extracts obtained from medicinal plants have proved to be useful for their wound healing properties. The aim of this study was to identify and validate the role of commonly used adjuvant compounds in… read more here.
Keywords: wound healing; chondroitin sulphate; chitosan chondroitin; sulphate agar ... See more keywords
Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules.
Sign Up to like & getrecommendations! Published in 2017 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2016.08.012
Abstract: OBJECTIVE To evaluate the anti-inflammatory mechanism of action of Chondroitin Sulphate (CS). DESIGN THP-1 macrophages were cultured with a range of sizes and concentrations of HA fragments with TLR4 (LPS in a physiologically relevant concentration… read more here.
Keywords: chondroitin sulphate; associated molecules; activity induced; damage associated ... See more keywords
Effect of chondroitin sulphate on synovitis of knee osteoarthritic patients.
Sign Up to like & getrecommendations! Published in 2017 at "Medicina Clinica"
DOI: 10.1016/j.medcle.2017.06.011
Abstract: Abstract Objective To evaluate by ultrasonography the effect of chondroitin sulfate (CS) on synovitis in patients with knee osteoarthritis (KOA). To collaborate in the understanding of the biochemical mechanisms involved in the synovial inflammation process.… read more here.
Keywords: chondroitin sulphate; synovitis; group; effect chondroitin ... See more keywords
Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1657753
Abstract: Chondroitin sulphate (CS) has long been used to treat osteoarthritis. Some investigations have also shown that the treatment with CS could reduce coronary events in patients with heart disease but no studies have identified the… read more here.
Keywords: chondroitin sulphate; knockout mice; apoe knockout;
Flaxseed extract reduces tissue accumulation and enhances urinary excretion of chondroitin sulphate in the rat: a possible new path in substrate reduction therapy for mucopolysaccharidosis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2068618
Abstract: Abstract Context Chondroitin 6 sulphate (C6S) is a glycosaminoglycan (GAG) whose accumulation is notable in mucopolysaccharidosis type IVA and VII. Flaxseed, Linum usitatissimum L. (Linaceae) (FS), is reported to have comparable properties to those of… read more here.
Keywords: flaxseed extract; chondroitin sulphate; accumulation; group ... See more keywords
Potential anti‐ageing effect of chondroitin sulphate through skin regeneration
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cosmetic Science"
DOI: 10.1111/ics.12645
Abstract: Skin ageing is inevitably exposed through its typical features such as wrinkles and sagging. Therefore, skin anti‐ageing is a major issue in cosmetic research to prevent and improve ageing symptoms using effective ingredients. Chondroitin sulphate… read more here.
Keywords: skin regeneration; chondroitin sulphate; skin; anti ageing ... See more keywords
Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes
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DOI: 10.1155/2018/9378515
Abstract: Background Diabetes mellitus is a global health problem representing the fifth leading cause of mortality and a major risk factor for cardiovascular diseases. In the last years, we reported an association among urinary trypsin inhibitor… read more here.
Keywords: chondroitin sulphate; trypsin inhibitor; type diabetes; type ... See more keywords
New Insights Into Human Hyaluronidase 4/Chondroitin Sulphate Hydrolase
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DOI: 10.3389/fcell.2021.767924
Abstract: In this review, the current experimental evidence, literature and hypotheses surrounding hyaluronidase 4 [HYAL4, also known as chondroitin sulphate hydrolase (CHSE)] and chondroitin sulphate (CS) are explored. Originally named for its sequence similarity to other… read more here.
Keywords: hyaluronidase; chondroitin sulphate; sulphate hydrolase; hyal4 ... See more keywords
Presence of chondroitin sulphate and requirement for heparan sulphate biosynthesis in the developing zebrafish inner ear
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DOI: 10.3389/fcell.2022.959624
Abstract: Epithelial morphogenesis to form the semicircular canal ducts of the zebrafish inner ear depends on the production of the large glycosaminoglycan hyaluronan, which is thought to contribute to the driving force that pushes projections of… read more here.
Keywords: zebrafish inner; inner ear; heparan sulphate; chondroitin sulphate ... See more keywords
Selective Inhibition of Heparan Sulphate and Not Chondroitin Sulphate Biosynthesis by a Small, Soluble Competitive Inhibitor
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22136988
Abstract: The glycosaminoglycan, heparan sulphate (HS), orchestrates many developmental processes. Yet its biological role has not yet fully been elucidated. Small molecule chemical inhibitors can be used to perturb HS function and these compounds provide cheap… read more here.
Keywords: chondroitin sulphate; heparan sulphate; sulphate; inhibition ... See more keywords