Chondroprotective effect of melatonin and strontium ranelate in animal model of osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06760
Abstract: Purpose To analyze the action of strontium ranelate (SR) and melatonin in isolation or in association in knees, liver and kidneys of rats Wistar with induced osteoarthritis (OA). Methods Thirty male rats were induced to… read more here.
Keywords: chondroprotective effect; strontium ranelate; association; liver kidneys ... See more keywords
60  Chondroprotective effect of an omega-3 fat supplement in a cartilage explant model of inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2021.103523
Abstract: Omega-3 fatty acid-enriched supplements (n3FAs) are commonly fed to horses for prevention of cartilage breakdown, though few have objective evidence for efficacy. Dietary n3FAs are metabolized to less inflammatory eicosanoids than their n6FA counterparts, and… read more here.
Keywords: chondroprotective effect; effect omega; cartilage; inflammation ... See more keywords
Evaluation of the Anti-Inflammatory and Chondroprotective Effect of Celecoxib on Cartilage Ex Vivo and in a Rat Osteoarthritis Model
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DOI: 10.1177/19476035221115541
Abstract: Objective The potential chondroprotective effect of celecoxib, a nonsteroidal anti-inflammatory drug and selective cyclooxygenase-2 inhibitor used to reduce pain and inflammation in knee osteoarthritis patients, is disputed. This study aimed at investigating the chondroprotective effects… read more here.
Keywords: celecoxib; cartilage; osteoarthritis; chondroprotective effect ... See more keywords
Microbial chondroitin sulfate in experimental knee osteoarthritis model investigation of chondroprotective effect.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202109_26647
Abstract: OBJECTIVE Chondroitin sulfate (CS) is a glycosaminoglycan with proven anti-inflammatory, anti-apoptotic, anti-oxidant properties. CS increases type II collagen and proteoglycan synthesis in human joint chondrocytes. CS can reduce the production of pro-inflammatory mediators and proteases… read more here.
Keywords: chondroprotective effect; chondroitin; chondroitin sulfate; model ... See more keywords
Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071733
Abstract: Intra-articular injections of glucocorticoids (GC) or hyaluronic acid (HA) are commonly used interventions for patients suffering from knee osteoarthritis (OA). Both substances are combined to achieve a chondroprotective and anti-inflammatory effect. Clinical studies have shown… read more here.
Keywords: culture; effect; chondroprotective effect; cytokine treated ... See more keywords