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   Articles with "chondrosarcoma" as a keyword



Circulating tumour DNA is a promising biomarker for risk stratification of central chondrosarcoma with IDH1/2 and GNAS mutations.

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recommendations! Published in 2021 at "Molecular oncology"

DOI: 10.1002/1878-0261.13102

Abstract: Chondrosarcoma (CS) is a rare tumour type and the most common primary malignant bone cancer in adults. The prognosis, currently based on tumour grade, imaging and anatomical location, is not reliable and more objective biomarkers… read more here.

Keywords: chondrosarcoma; ctdna; tumour dna; circulating tumour ... See more keywords

Familial solitary chondrosarcoma resulting from germline EXT2 mutation

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recommendations! Published in 2017 at "Genes"

DOI: 10.1002/gcc.22419

Abstract: Germline mutations of EXT2, encoding Exostosin Glycosyltransferase 2, are associated with multiple osteochondromas (MO), an autosomal dominant disease characterized by the development of multiple peripheral cartilaginous benign tumors with a weak risk of malignant transformation.… read more here.

Keywords: chondrosarcoma; germline ext2; ext2 mutation; development ... See more keywords

The Impact of Chondrosarcoma with Positive Margins and Extraosseous Extension on Patient Outcomes

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recommendations! Published in 2024 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.27982

Abstract: Chondrosarcoma accounts for 20% of all bony sarcomas and may present with extraosseous extension (EOE). The presence of an extraosseous component, along with positive surgical margins, has been separately associated with increased risk of local… read more here.

Keywords: impact chondrosarcoma; extraosseous extension; chondrosarcoma positive; positive margins ... See more keywords

Chondrosarcoma of the Flat Bones: Differential Survival Between High‐Grade Lesions of the Pelvis and Scapula

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recommendations! Published in 2024 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.28023

Abstract: Flat bone chondrosarcomas have worse outcomes than extremity tumors, but there is no data directly comparing the different flat bones. The aim of this study was to examine differences in recurrence and survival between pelvic… read more here.

Keywords: survival high; bones differential; chondrosarcoma flat; flat bones ... See more keywords

Basic fibroblast growth factor promotes doxorubicin resistance in chondrosarcoma cells by affecting XRCC5 expression

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recommendations! Published in 2020 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23153

Abstract: Chondrosarcoma is the second most common form of bone cancer and is characterized by its ability to produce an extracellular matrix of the cartilage. High‐grade chondrosarcoma is highly aggressive and can metastasize to other parts… read more here.

Keywords: chondrosarcoma; fibroblast growth; chondrosarcoma cells; resistance ... See more keywords

Intralesional vs. extralesional procedures for low-grade central chondrosarcoma: a systematic review of the literature

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recommendations! Published in 2018 at "Archives of Orthopaedic and Trauma Surgery"

DOI: 10.1007/s00402-018-2930-0

Abstract: IntroductionChondroid lesions are very common bone tumors. In most cases, they are benign enchondromas (EC) and, in a minor percentage, chondrosarcomas (CSs), the malignant counterpart. In the latter cases, surgery is the mainstay treatment, because… read more here.

Keywords: chondrosarcoma; review literature; low grade; resection ... See more keywords

Angiogenesis-Targeted 68Ga-DOTA-RGD2 PET/CT Imaging: a Potential Theranostic Application in the Case of Chondrosarcoma

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recommendations! Published in 2021 at "Nuclear Medicine and Molecular Imaging"

DOI: 10.1007/s13139-021-00691-w

Abstract: Chondrosarcoma is a cartilaginous tumor of mesenchymal origin. The histology and grade of the tumor determine the chances of relapse and survival. These tumors usually respond poorly to chemo-radiotherapy in cases of non-resectable and recurrent… read more here.

Keywords: chondrosarcoma; 68ga dota; pet; angiogenesis ... See more keywords

Coexistence of secondary chondrosarcoma and lung carcinoma metastasis in the humerus of a patient with Ollier's disease: A case report

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recommendations! Published in 2019 at "Acta Orthopaedica et Traumatologica Turcica"

DOI: 10.1016/j.aott.2018.10.008

Abstract: Tumor-to-tumor metastasis in the same bone is an extremely rare condition. Limited number of case reports exists for coincidence of benign and malign neoplasms but none for malignant to malignant metastasis. Occurrence of several individual… read more here.

Keywords: chondrosarcoma; ollier disease; case; metastasis ... See more keywords

The diagnostic significance of pulmonary nodules on CT thorax in chondrosarcoma of bone.

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recommendations! Published in 2019 at "Clinical radiology"

DOI: 10.1016/j.crad.2019.11.017

Abstract: AIM To provide a diagnostic approach to pulmonary nodules in patients with chondrosarcoma. MATERIALS AND METHODS A search of the oncology database at a specialist orthopaedic oncology referral centre was performed to identify all patients… read more here.

Keywords: chondrosarcoma; diagnostic significance; pulmonary nodules; patients grade ... See more keywords

Renal Extra Skeletal Mesenchymal Chondrosarcoma: A Case Report

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recommendations! Published in 2017 at "Urology Case Reports"

DOI: 10.1016/j.eucr.2016.12.013

Abstract: Primary mesenchymal chondrosarcoma of the Kidney is an extremely rare entity and very few cases have been reported in literature. We report a 22-year-old male with a right renal mass; after radical nephrectomy, pathologic examination… read more here.

Keywords: chondrosarcoma; skeletal mesenchymal; extra skeletal; report ... See more keywords

Minute mesenchymal chondrosarcoma within osteochondroma: an unexpected diagnosis confirmed by HEY1-NCOA2 fusion.

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recommendations! Published in 2018 at "Human pathology"

DOI: 10.1016/j.humpath.2018.03.014

Abstract: Mesenchymal chondrosarcoma is rare and can be challenging to diagnose. Herein, we report a minute mesenchymal chondrosarcoma within an osteochondroma. A 12-year-old girl presented with an asymptomatic exophytic lesion of the rib. The tumor was… read more here.

Keywords: chondrosarcoma; within osteochondroma; chondrosarcoma within; mesenchymal chondrosarcoma ... See more keywords