The regulation of cellular apoptosis by the ROS‐triggered PERK/EIF2&agr;/chop pathway plays a vital role in bisphenol A‐induced male reproductive toxicity
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2016.11.013
Abstract: Abstract Bisphenol A (2,2‐bis(4‐hydroxyphenyl)propane, BPA) is ubiquitous in the environment, wildlife, and humans. Evidence from past studies suggests that BPA is associated with decreased semen quality. However, the molecular basis for the adverse effect of… read more here.
Keywords: bpa; perk eif2; agr chop; eif2 agr ... See more keywords
Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells
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DOI: 10.3390/nu14163356
Abstract: Riboflavin is an essential micronutrient and a precursor of flavin mononucleotide and flavin adenine dinucleotide for maintaining cell homeostasis. Riboflavin deficiency (RD) induces cell apoptosis. Endoplasmic reticulum (ER) stress is considered to induce apoptosis, and… read more here.
Keywords: cell; stress; apoptosis; chop pathway ... See more keywords
A marine-derived small molecule induces immunogenic cell death against triple-negative breast cancer through ER stress-CHOP pathway
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DOI: 10.7150/ijbs.70975
Abstract: Although triple-negative breast cancer (TNBC) is the most refractory subtype among all breast cancers, it has been shown to have higher immune infiltration than other subtypes. We identified the marine-derived small molecule MHO7, which acts… read more here.
Keywords: stress; cell; chop pathway; breast ... See more keywords