Rolipram suppresses migration and invasion of human choriocarcinoma cells by inhibiting phosphodiesterase 4-mediated epithelial-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23363
Abstract: Rolipram is a selective phosphodiesterase-4 (PDE4) inhibitor. The effect of rolipram on the metastasis of choriocarcinoma is barely known. Here, we evaluated the role of rolipram in the migration and invasion of human choriocarcinoma cells… read more here.
Keywords: choriocarcinoma cells; choriocarcinoma; rolipram; migration invasion ... See more keywords
Lidocine potentiates the cytotoxicity of 5‐fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28913
Abstract: Choriocarcinoma is a gestational trophoblastic cancer, which often occurs in the first 3 months of pregnancy. 5‐Fluorouracil (5‐Fu) is the widely used chemotherapeutic drug for choriocarcinoma but limited by drug resistance. Lidocaine, an aminamide‐type anesthetic,… read more here.
Keywords: jeg jar; choriocarcinoma; cells downregulating; cytotoxicity ... See more keywords
Inhibitory Effects of Quercetin on Progression of Human Choriocarcinoma Cells Are Mediated Through PI3K/AKT and MAPK Signal Transduction Cascades
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25637
Abstract: As a major dietary flavonol, quercetin mitigates proliferation and progression of cancer due to its anti‐angiogenic, anti‐inflammatory, anti‐oxidant, and apoptotic biological effects on cells. Although its apoptotic effects have been reported for various cancers, little… read more here.
Keywords: jeg3 cells; choriocarcinoma; jar jeg3; mapk signal ... See more keywords
Chrysin disrupts intracellular homeostasis through mitochondria-mediated cell death in human choriocarcinoma cells.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.109
Abstract: The trophoblast cells which form the placenta, have a high potential for invading other tissues. Owing to certain mechanisms, trophoblast cells may lose their ability to control cell proliferation, and develop into pregnancy-related tumors, known… read more here.
Keywords: chrysin disrupts; choriocarcinoma; intracellular homeostasis; disrupts intracellular ... See more keywords
Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.04.014
Abstract: Myricetin is a bioactive compound found in a variety of vegetables and fruits, and its anti-cancer effects are well known. In this study, we confirmed that myricetin reduced proliferation of two choriocarcinoma cell lines (JAR… read more here.
Keywords: human placental; choriocarcinoma cells; myricetin; jar jeg ... See more keywords
Involvement of l-type amino acid transporter 1 in the transport of gabapentin into human placental choriocarcinoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2016.11.002
Abstract: Gabapentin (GBP) is a widely used antiepileptic drug, with potential for use in the treatment of epilepsy in pregnant women. Although studies have examined GBP transport mechanisms across the blood-brain barrier, kidney, and intestine, the… read more here.
Keywords: type amino; transport; human placental; placental choriocarcinoma ... See more keywords
α,β-Thujone suppresses human placental choriocarcinoma cells via metabolic disruption.
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction"
DOI: 10.1530/rep-20-0018
Abstract: α,β-Thujone is a natural terpenoid found in many medicinal herbs, such as Artemisia absinthium (wormwood), that exhibits antioxidant, anti-diabetic, and anti-tumorigenic effects. α,β-Thujone has numerous functions; it serves as a food ingredient, cosmetic additive, and… read more here.
Keywords: placental choriocarcinoma; thujone; choriocarcinoma cells; thujone suppresses ... See more keywords