Abstract 3582: Inclusion of a Dap10 costimulatory domain enhances anti-tumor efficacy of chimeric PD1-expressing T cells in multiple types of solid tumors
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DOI: 10.1158/1538-7445.am2018-3582
Abstract: Adoptive transfer of tumor-reactive T cells is a promising anti-tumor therapy for many cancers. To enhance tumor recognition by T cells, chimeric antigen receptors (CAR) consisting of signaling domains fused to receptors that recognize tumor… read more here.
Keywords: chpd1; costimulatory; anti tumor; receptor ... See more keywords