Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1710849115
Abstract: Significance The mechanisms of chromophobe renal cell carcinoma (ChRCC) pathogenesis remain a key knowledge gap. Through metabolomics, this study uncovered a fundamental metabolic mechanism underlying the pathogenesis of ChRCC, with key therapeutic implications for this… read more here.
Keywords: renal cell; cell carcinoma; chrcc; chromophobe renal ... See more keywords
The Critical Gene Screening to Prevent Chromophobe Cell Renal Carcinoma Metastasis through TCGA and WGCNA
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2909095
Abstract: Common chromophobe renal cell carcinoma (chRCC) has a good prognosis when cured by surgery. However, clinical practice shows that a small number of patients with chRCC will produce metastasis, and the prognosis after metastasis is… read more here.
Keywords: metastasis; cell; chrcc; gene ... See more keywords
Chromophobe renal cell carcinoma – a rare kidney cancer with limited therapy options: a narrative review
Sign Up to like & getrecommendations! Published in 2025 at "BMC Urology"
DOI: 10.1186/s12894-025-01816-5
Abstract: Chromophobe renal cell carcinoma (chRCC) is a rare subtype of renal cell carcinoma (RCC) and is the most common form of non-clear cell renal cell carcinoma in young women. Compared to clear cell renal cell… read more here.
Keywords: chrcc; review; cell; cell carcinoma ... See more keywords
Single-center analysis of 109 patients (pts) with metastatic chromophobe renal cell carcinoma (ChRCC): Differences in outcomes by histologic variant.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.4577
Abstract: 4577Background: ChRCC constitutes 5-10% of all RCC cases, and is generally associated with better prognosis including benefit from approved targeted agents (Armstrong, Lancet Onc, 2016). Presence o... read more here.
Keywords: single center; 109 patients; analysis 109; chrcc ... See more keywords
Investigation of ferroptosis and mTOR signaling in chromophobe renal cell carcinoma (ChRCC).
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.5_suppl.583
Abstract: 583 Background: ChRCC is a rare form of kidney cancer that has shown limited response to immune checkpoint inhibitors currently used as the standard-of-care for other RCC histologies. mTOR inhibition is a therapeutic strategy for… read more here.
Keywords: ferroptosis mtor; cell; mtor; chrcc ... See more keywords
Prognostic Values of E2F1/2 Transcriptional Expressions in Chromophobe Renal Cell Carcinoma Patients: Evidence from Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s321585
Abstract: Background Numerous studies on the E2F transcription factors have led to increasing insights that E2Fs could be an important driver of the formation and progression of many human cancers. Little is known about the function… read more here.
Keywords: expression; e2fs; chromophobe renal; e2f1 ... See more keywords
Histological differential diagnostics of renal oncocytoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental oncology"
DOI: 10.32471/exp-oncology.2312-8852.vol-42-no-3.14968
Abstract: BACKGROUND The morbidity rate of kidney cancer has been increasing. Management of patients and their prognosis depend on the specific histological type of tumor. Unfortunately, different renal tumors can have similar histological features, making differential… read more here.
Keywords: differential diagnostics; diagnosis; histological differential; chrcc ... See more keywords
Use of specific contrast-enhanced CT regions of interest to differentiate renal oncocytomas from small clear cell and chromophobe renal cell carcinomas
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostic and Interventional Radiology"
DOI: 10.5152/dir.2022.2111504
Abstract: PURPOSE We aimed to examine the usefulness of utilizing a specific contrast-enhanced computed tomography (CT) region of interest (ROI) to differentiate renal oncocytoma (RO) from small clear cell renal cell carcinoma (ccRCC) and chromophobe renal… read more here.
Keywords: cell; chrcc; ccrcc; roi ... See more keywords