LncRNA CHRF aggravates myocardial ischemia/reperfusion injury by enhancing autophagy via modulation of the miR‐182‐5p/ATG7 pathway
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22709
Abstract: Myocardial ischemia/reperfusion (I/R) injury is a very frequent cardiovascular disease and one of the leading causes of death. Abundant evidence has shown that long noncoding RNAs (lncRNAs) are crucial players in myocardial I/R injury. LncRNA… read more here.
Keywords: mir 182; chrf; myocardial injury; myocardial ischemia ... See more keywords
Long noncoding RNA CHRF exacerbates IL‐6‐induced inflammatory damages by downregulating microRNA‐146a in ATDC5 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28749
Abstract: Osteoarthritis (OA) is a frequent chronic musculoskeletal disorder which lacks applicably effective therapeutic strategy. In this study, we attempted to investigate whether long noncoding RNA (lncRNA) cardiac hypertrophy‐related factor (CHRF) participated in mediating interleukin‐6 (IL‐6)‐induced… read more here.
Keywords: long noncoding; lncrna chrf; atdc5 cells; noncoding rna ... See more keywords
Long non-coding RNA CHRF modulates the progression of cerebral ischemia/reperfusion injury via miR-126/SOX6 signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.161
Abstract: Ischemic stroke remains as a major cause for disability and death in the world. Long non-coding RNA (lncRNA) cardiac hypertrophy-related factor (CHRF) has been suggested as a crucial modulator in cardiac injury and various human… read more here.
Keywords: mir 126; chrf; rna; long non ... See more keywords
Novel role of lncRNA CHRF in cisplatin resistance of ovarian cancer is mediated by miR-10b induced EMT and STAT3 signaling
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DOI: 10.1038/s41598-020-71153-0
Abstract: Ovarian Cancer (OC) is a highly lethal gynecological cancer which often progresses through acquired resistance against the administered therapy. Cisplatin is a common therapeutic for the treatment of OC patients and therefore it is critical… read more here.
Keywords: mir 10b; chrf; resistance; cancer ... See more keywords
IL-1β-Triggered Long Non-coding RNA CHRF Induces Non-Small Cell Lung Cancer by Modulating the microRNA-489/Myd88 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer"
DOI: 10.7150/jca.63256
Abstract: Background: Long noncoding RNAs (LncRNAs) possess crucial roles in carcinogenesis. The current study aims to evaluate the effects of interleukin-1β (IL-1β)-mediated lncRNA cardiac hypertrophy-related factor (CHRF)/microRNA-489 (miR-489)/myeloid differentiation factor 88 (Myd88) on non-small-cell lung cancer… read more here.
Keywords: cell; 489 myd88; lncrna chrf; mir 489 ... See more keywords