Schwann cell precursors generate sympathoadrenal system during zebrafish development
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24909
Abstract: The autonomic portion of the peripheral nervous system orchestrates tissue homeostasis through direct innervation of internal organs, and via release of adrenalin and noradrenalin into the blood flow. The developmental mechanisms behind the formation of… read more here.
Keywords: cell precursors; chromaffin cells; system; schwann cell ... See more keywords
Measurements of Exocytosis by Capacitance Recordings and Calcium Uncaging in Mouse Adrenal Chromaffin Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1044-2_16
Abstract: Fusion of vesicles with the plasma membrane and liberation of their contents is a multistep process involving several proteins. Correctly assigning the role of specific proteins and reactions in this cascade requires a measurement method… read more here.
Keywords: adrenal chromaffin; chromaffin cells; calcium uncaging; capacitance ... See more keywords
Measurements of Compensatory Endocytosis by Antibody Internalization and Quantification of Endocytic Vesicle Distribution in Adrenal Chromaffin Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1044-2_3
Abstract: Plasma membrane proteins are amenable to endocytosis assays since they are easily labeled by reagents applied in the extracellular medium. This has been widely exploited to study constitutive endocytosis or ligand-induced receptor endocytosis. Compensatory endocytosis… read more here.
Keywords: chromaffin cells; vesicle; antibody; endocytosis ... See more keywords
Fusion Pore Selectivity in Chromaffin Cells
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2148
Abstract: Healthy physiological conditions depend on dynamic release of neurotransmitters and hormones by exocytosis, which is initiated by the fusion pore. Previous studies show that reduction of extracellular [NaCl] decreases the amperometric foot current, indicating no… read more here.
Keywords: chromaffin cells; foot current; fusion; fusion pore ... See more keywords
Human native Cav1 channels in chromaffin cells: contribution to exocytosis and firing of spontaneous action potentials
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2016.12.009
Abstract: ABSTRACT The present study was performed to evaluate the Cav1 channel subtypes expressed in human chromaffin cells and the role that these channels play in exocytosis and cell excitability. Here we show that human chromaffin… read more here.
Keywords: chromaffin cells; contribution; spontaneous action; cav1 ... See more keywords
Differential Co-release of Two Neurotransmitters from a Vesicle Fusion Pore in Mammalian Adrenal Chromaffin Cells
Sign Up to like & getrecommendations! Published in 2019 at "Neuron"
DOI: 10.1016/j.neuron.2019.01.031
Abstract: Co-release of multiple neurotransmitters from secretory vesicles is common in neurons and neuroendocrine cells. However, whether and how the transmitters co-released from a single vesicle are differentially regulated remains unknown. In matrix-containing dense-core vesicles (DCVs)… read more here.
Keywords: chromaffin cells; quantal release; fusion; sub quantal ... See more keywords
Preformed Ω-profile closure and kiss-and-run mediate endocytosis and diverse endocytic modes in neuroendocrine chromaffin cells
Sign Up to like & getrecommendations! Published in 2021 at "Neuron"
DOI: 10.1016/j.neuron.2021.07.019
Abstract: Transformation of flat membrane into round vesicles is generally thought to underlie endocytosis and produce speed-, amount-, and vesicle-size-specific endocytic modes. Visualizing depolarization-induced exocytic and endocytic membrane transformation in live neuroendocrine chromaffin cells, we found… read more here.
Keywords: neuroendocrine chromaffin; endocytic modes; chromaffin cells; transformation ... See more keywords
The Vesicular Transmitter Content in Chromaffin Cells can be Regulated via Extracellular ATP.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00494
Abstract: The energy carrying molecule adenosine triphosphate (ATP) has been implicated for its role in modulation of chemical signaling for some time. Despite this, the precise effects and mechanisms of action of ATP on secretory cells… read more here.
Keywords: vesicular transmitter; chromaffin cells; atp; extracellular atp ... See more keywords
Altered exocytosis in chromaffin cells from mouse models of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2018 at "Acta Physiologica"
DOI: 10.1111/apha.13090
Abstract: Chromaffin cells from the adrenal gland (CCs) have extensively been used to explore the molecular structure and function of the exocytotic machinery, neurotransmitter release and synaptic transmission. The CC is integrated in the sympathoadrenal axis… read more here.
Keywords: models neurodegenerative; mouse models; chromaffin cells; exocytotic events ... See more keywords
The firing frequency of spontaneous action potentials and their corresponding evoked exocytosis are increased in chromaffin cells of CCl4‐induced cirrhotic rats with respect to control rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14618
Abstract: High catecolamine plasma levels because of sympathetic nervous system over‐activity contribute to cirrhosis progression. The aim of this study was to investigate whether chromaffin cells of the adrenal gland might potentiate the deleterious effect exerted… read more here.
Keywords: chromaffin cells; control; cirrhotic rats; induced cirrhotic ... See more keywords
The Ca2+ channel subunit CaVβ2a‐subunit down‐regulates voltage‐activated ion current densities by disrupting actin‐dependent traffic in chromaffin cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14851
Abstract: β‐Subunits of the Ca2+ channel have been conventionally regarded as auxiliary subunits that regulate the expression and activity of the pore‐forming α1 subunit. However, they comprise protein–protein interaction domains, such as a SRC homology 3… read more here.
Keywords: chromaffin cells; sh3; ca2 channel; subunit ... See more keywords