Analysis of Meiotic Sister Chromatid Cohesion in Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6545-8_5
Abstract: In sexually reproducing organisms, the formation of healthy gametes (sperm and eggs) requires the proper establishment and release of meiotic sister chromatid cohesion (SCC). SCC tethers replicated sisters from their formation in premeiotic S phase… read more here.
Keywords: cohesion; chromatid cohesion; sister chromatid; meiotic sister ... See more keywords
Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-12-0853
Abstract: HPV-transforming protein E6 weakens both SAC activity and sister chromatid cohesion. These processes largely function normally and result in chromosome segregation errors only when mitosis is delayed by the presence of one to four unaligned,… read more here.
Keywords: chromatid cohesion; sister chromatid; hpv;
Preprint Highlight: Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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DOI: 10.1091/mbc.p23-03-0010
Abstract: Cohesins organize chromatin within the nucleus by promoting loop extrusion via cis contacts on chromatin and sister chromatid cohesion via trans contacts between chromatids. Whether cohesins employ a distinct mechanism for these two functions is… read more here.
Keywords: extrusion; sister chromatid; chromatid cohesion; loop extrusion ... See more keywords
The cohesin complex of yeasts: sister chromatid cohesion and beyond.
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DOI: 10.1093/femsre/fuac045
Abstract: Each time a cell divides, it needs to duplicate the genome and then separate the two copies. In eukaryotes, which usually have more than one linear chromosome, this entails tethering the two newly replicated DNA… read more here.
Keywords: cohesin; chromatid cohesion; chromosome; sister chromatid ... See more keywords
Reduced sister chromatid cohesion acts as a tumor penetrance modifier
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DOI: 10.1371/journal.pgen.1010341
Abstract: Sister chromatid cohesion (SCC) is an important process in chromosome segregation. ESCO2 is essential for establishment of SCC and is often deleted/altered in human cancers. We demonstrate that esco2 haploinsufficiency results in reduced SCC and… read more here.
Keywords: tumor penetrance; chromatid cohesion; sister chromatid;