Comprehensive analysis of nonsurrounded nucleolus and surrounded nucleolus oocytes on chromatin accessibility using ATAC‐seq
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23668
Abstract: Mouse germinal vesicle (GV) oocytes are divided into surrounded nucleolus (SN) and nonsurrounded nucleolus (NSN) oocytes based on chromatin morphology. NSN oocytes spontaneously transform into SN oocytes after accumulating enough maternal transcripts. SN oocytes show… read more here.
Keywords: nsn oocytes; surrounded nucleolus; accessibility; nonsurrounded nucleolus ... See more keywords
Single-Molecule Multikilobase-Scale Profiling of Chromatin Accessibility Using m6A-SMAC-Seq and m6A-CpG-GpC-SMAC-Seq.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2140-0_15
Abstract: A hallmark feature of active cis-regulatory elements (CREs) in eukaryotes is their nucleosomal depletion and, accordingly, higher accessibility to enzymatic treatment. This property has been the basis of a number of sequencing-based assays for genome-wide… read more here.
Keywords: chromatin accessibility; smac seq; single molecule; seq ... See more keywords
373P Chromatin accessibility reveals potential prognostic value of the peak set associated with smoking history in patients with lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Oncology"
DOI: 10.1016/j.annonc.2020.10.366
Abstract: K. Prabhash, A.R. Jazieh, H.C. Onal, D.S. Weng Tan, R.A. Soo, A. Kumar, R. Huggenberger, S. Robb, B.C. Cho Medical Onclogy Department, Tata Memorial Hospital, Mumbai, India; Department of Oncology, King Abdullah International Medical Research… read more here.
Keywords: accessibility reveals; potential prognostic; 373p chromatin; chromatin accessibility ... See more keywords
Chromatin Accessibility Studied by Slow Scan FCS in the Eukaryotic Nucleus
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1195
Abstract: DNA is one of the most important biological macromolecules, since it harbors the genetic information of the cell. In order to fit in eukaryotic cell nucleus, DNA is highly compacted and packed by histones in… read more here.
Keywords: accessibility; slow scan; chromatin accessibility; cell ... See more keywords
HDAC Inhibitors Finally Open Up: Chromatin Accessibility Signatures of CTCL.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.06.008
Abstract: In this issue of Cancer Cell, Qu et al. describe the chromatin accessibility profiles of cutaneous T cell lymphoma, with dynamic assessments of response and resistance to histone deacetylase inhibitor therapy. Their "personal regulome" analysis framework reveals… read more here.
Keywords: finally open; hdac inhibitors; accessibility; open chromatin ... See more keywords
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.09.056
Abstract: Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process precluding a temporal understanding of regulatory events… read more here.
Keywords: single cell; chromatin; chromatin accessibility; chromatin potential ... See more keywords
Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108180
Abstract: SUMMARY Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive. Here, we analyze global chromatin accessibility profiles across resting and stimulated human… read more here.
Keywords: chromatin; heterogeneity; chromatin landscape; chromatin accessibility ... See more keywords
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.03.007
Abstract: Summary Murine regulatory T (Treg) cells in tissues promote tissue homeostasis and regeneration. We sought to identify features that characterize human Treg cells with these functions in healthy tissues. Single-cell chromatin accessibility profiles of murine… read more here.
Keywords: single cell; treg cells; tissue; chromatin accessibility ... See more keywords
Considerations in the analysis of plant chromatin accessibility data.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2020.01.003
Abstract: Transcriptional control is exerted primarily through the binding of transcription factor proteins to regulatory elements in DNA. By virtue of eukaryotic DNA being complexed with histones, transcription factor binding to DNA alters or eliminates histone-DNA… read more here.
Keywords: chromatin accessibility; plant chromatin; accessibility; dna ... See more keywords
Chromatin Accessibility Dynamics during iPSC Reprogramming.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2017.10.012
Abstract: Cell-fate decisions remain poorly understood at the chromatin level. Here, we map chromatin remodeling dynamics during induction of pluripotent stem cells. ATAC-seq profiling of MEFs expressing Oct4-Sox2-Klf4 (OSK) reveals dynamic changes in chromatin states shifting… read more here.
Keywords: dynamics ipsc; chromatin; chromatin accessibility; ipsc reprogramming ... See more keywords
Chromatin accessibility and histone acetylation in the regulation of competence in early development.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental biology"
DOI: 10.1016/j.ydbio.2020.02.013
Abstract: As development proceeds, inductive cues are interpreted by competent tissues in a spatially and temporally restricted manner. While key inductive signaling pathways within competent cells are well-described at a molecular level, the mechanisms by which… read more here.
Keywords: chromatin accessibility; competence; histone; development ... See more keywords