Disruption of CDK-resistant chromatin association by pRB causes DNA damage, mitotic errors, and reduces Condensin II recruitment
Sign Up to like & getrecommendations! Published in 2017 at "Cell Cycle"
DOI: 10.1080/15384101.2017.1338984
Abstract: ABSTRACT Organization of chromatin structure is indispensible to the maintenance of genome integrity. The retinoblastoma tumor suppressor protein (pRB) mediates both transcriptional repression and chromatin organization, but the independent contributions of these functions have been… read more here.
Keywords: chromatin; cdk resistant; chromatin association; prb ... See more keywords
Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2
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DOI: 10.1091/mbc.e16-08-0573
Abstract: DDB2 is a multifunctional protein that participates in both nucleotide excision repair and regulation of gene transcription. In colon cancer cells, chromatin association of XRCC5/6, in the absence of DNA damage, depends on DDB2, and… read more here.
Keywords: dna damage; xrcc5 absence; absence dna; association xrcc5 ... See more keywords
Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association
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DOI: 10.26508/lsa.201800270
Abstract: This study suggests a novel role of the telomere-associated human CST complex in suppressing origin licensing, through interactions with MCM, while promoting the recruitment of AND-1 and DNA polymerase alpha for replisome formation. Human CTC1-STN1-TEN1… read more here.
Keywords: cst; human cst; origin licensing; replication ... See more keywords