Pentad: a tool for distance-dependent analysis of Hi-C interactions within and between chromatin compartments
Sign Up to like & getrecommendations! Published in 2022 at "BMC Bioinformatics"
DOI: 10.1186/s12859-022-04654-6
Abstract: Background Understanding the role of various factors in 3D genome organization is essential to determine their impact on shaping large-scale chromatin units such as euchromatin (A) and heterochromatin (B) compartments. At this level, chromatin compaction… read more here.
Keywords: chromatin; distance dependent; pentad tool; chromatin compartments ... See more keywords
A Liquid State Perspective on Dynamics of Chromatin Compartments
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.781981
Abstract: The interior of the eukaryotic cell nucleus has a crowded and heterogeneous environment packed with chromatin polymers, regulatory proteins, and RNA molecules. Chromatin polymer, assisted by epigenetic modifications, protein and RNA binders, forms multi-scale compartments… read more here.
Keywords: chromatin compartments; dynamics chromatin; perspective dynamics; liquid state ... See more keywords
Considerations and caveats for analyzing chromatin compartments
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1168562
Abstract: Genomes are organized into nuclear compartments, separating active from inactive chromatin. Chromatin compartments are readily visible in a large number of species by experiments that map chromatin conformation genome-wide. When analyzing these maps, a common… read more here.
Keywords: chromatin compartments; considerations caveats; analyzing chromatin; chromatin ... See more keywords