The DEAD-box helicase eIF4A1/2 acts as RNA chaperone during mitotic exit enabling chromatin decondensation
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-57592-1
Abstract: During mitosis, chromosomes condense and decondense to segregate faithfully and undamaged. The exact molecular mechanisms are not well understood. We identify the DEAD-box helicase eIF4A1/2 as a critical factor in this process. In a cell-free… read more here.
Keywords: chromatin decondensation; decondensation; dead box; helicase eif4a1 ... See more keywords
In vitro effects of endosulfan-based insecticides on mammalian sperm.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology research"
DOI: 10.1039/c7tx00251c
Abstract: Endosulfan is an organochloride insecticide extensively used in several countries to protect crops from pests. As several studies indicate that endosulfan can affect human and animal development, the aim of this study was to analyse… read more here.
Keywords: decondensation; vitro effects; chromatin decondensation; sperm ... See more keywords