LAP2β transmits force to upregulate genes via chromatin domain stretching but not compression.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.10.029
Abstract: There is increasing evidence that force impacts almost every aspect of cells and tissues in physiology and disease including gene regulation. However, the molecular pathway of force transmission from the nuclear lamina to the chromatin… read more here.
Keywords: chromatin; gene; chromatin domain; force transmission ... See more keywords