Chromatin Fiber Invasion and Nucleosome Displacement by the Rap1 Transcription Factor
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cell"
DOI: 10.1016/j.molcel.2019.10.025
Abstract: Summary Pioneer transcription factors (pTFs) bind to target sites within compact chromatin, initiating chromatin remodeling and controlling the recruitment of downstream factors. The mechanisms by which pTFs overcome the chromatin barrier are not well understood.… read more here.
Keywords: chromatin; transcription factor; chromatin fiber; rap1 ... See more keywords
Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells
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DOI: 10.7554/elife.72062
Abstract: A longstanding hypothesis is that chromatin fiber folding mediated by interactions between nearby nucleosomes represses transcription. However, it has been difficult to determine the relationship between local chromatin fiber compaction and transcription in cells. Further,… read more here.
Keywords: chromatin; represses transcription; chromatin fiber; fiber folding ... See more keywords