Quantitative telomeric chromatin isolation protocol for human cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods"
DOI: 10.1016/j.ymeth.2016.08.003
Abstract: The ends of eukaryotic chromosomes, known as telomeres, consist of repetitive DNA sequences, multiple proteins and noncoding RNAs. Telomeres are dynamic structures that play crucial roles as guardians of genome stability and tumor suppressors. Defects… read more here.
Keywords: chromatin isolation; telomeric chromatin; isolation protocol; quantitative telomeric ... See more keywords
Locus-specific chromatin isolation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-020-0217-0
Abstract: Identifying factors bound to specific genomic loci in an unbiased manner is the holy grail of chromatin research, because it would provide an ultimate description of locus function. In this Comment, we explain why purifying… read more here.
Keywords: chromatin isolation; chromatin; locus specific; specific chromatin ... See more keywords