Chromatin remodelers in oligodendroglia
Sign Up to like & getrecommendations! Published in 2020 at "Glia"
DOI: 10.1002/glia.23837
Abstract: Oligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which… read more here.
Keywords: remodelers oligodendroglia; chromatin; chromatin remodelers; chromatin remodeling ... See more keywords
Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.10.005
Abstract: Mammalian SWI/SNF (BAF) chromatin remodelers play dosage-sensitive roles in many human malignancies and neurologic disorders. The gene encoding the BAF subunit actin-like 6a (ACTL6A) is amplified early in the development of many squamous cell carcinomas… read more here.
Keywords: squamous cell; baf; actl6a occupancy; increased actl6a ... See more keywords
Nuclear actin switch of the INO80 remodeler
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjy083
Abstract: Eukaryotic DNA is wrapped in nucleosomes, which impede the access of transcription factors and regulatory proteins to template DNA. Chromatin remodelers utilize the energy from ATP hydrolysis to drive histone movement relative to nucleosomal DNA… read more here.
Keywords: ino80; dna; willhoft 2018; switch ... See more keywords
Transcription elongator SPT6L regulates the occupancies of the SWI2/SNF2 chromatin remodelers SYD/BRM and nucleosomes at transcription start sites in Arabidopsis
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1126
Abstract: Abstract Chromatin remodelers have been thought to be crucial in creating an accessible chromatin environment before transcription activation. However, it is still unclear how chromatin remodelers recognize and bind to the active regions. In this… read more here.
Keywords: syd brm; chromatin remodelers; spt6l; chromatin ... See more keywords
Evaluation of chromatin remodelers in pancreatic neuroendocrine neoplasms.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2023.41.4_suppl.652
Abstract: 652 Background: Pancreatic neuroendocrine neoplasms (PanNENs) are rare entities comprising 1-2% of gastroenteropancreatic neoplasms with an annual incidence of 0.48/100,000 population in the world. The molecular pathways underpinning the entity are less explored owing to… read more here.
Keywords: loss; expression; chromatin remodelers; neuroendocrine neoplasms ... See more keywords