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   Articles with "chromatin remodeling" as a keyword



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Chromatin remodelers in oligodendroglia

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recommendations! Published in 2020 at "Glia"

DOI: 10.1002/glia.23837

Abstract: Oligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which… read more here.

Keywords: remodelers oligodendroglia; chromatin; chromatin remodelers; chromatin remodeling ... See more keywords
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Differential expression of key subunits of SWI/SNF chromatin remodeling complexes in porcine embryos derived in vitro or in vivo

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recommendations! Published in 2017 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.22922

Abstract: In vitro embryo production is an established method for both humans and animals, but is fraught with inferior development and health issues in offspring born after in vitro fertilization procedures. Analysis of epigenetic changes caused… read more here.

Keywords: differential expression; chromatin remodeling; expression key; chromatin ... See more keywords

Chromatin Remodeling Factor BRG1 Regulates Stemness and Chemosensitivity of Glioma Initiating Cells

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recommendations! Published in 2018 at "STEM CELLS"

DOI: 10.1002/stem.2909

Abstract: Glioblastoma multiforme (GBM) is a highly aggressive and malignant brain tumor that is refractory to existing therapeutic regimens, which reflects the presence of stem‐like cells, termed glioma‐initiating cells (GICs). The complex interactions between different signaling… read more here.

Keywords: brg1; chromatin remodeling; stemness chemosensitivity; initiating cells ... See more keywords

Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.

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recommendations! Published in 2021 at "Environmental pollution"

DOI: 10.1016/j.envpol.2021.117446

Abstract: Researches have shown that silica nanoparticles (SiNPs) could reduce both the quantity and quality of sperm. However, the mechanism of toxicity induced by SiNPs in the male reproductive system is still unclear. In this study,… read more here.

Keywords: rnf8; chromatin remodeling; group; silica nanoparticles ... See more keywords

MafK mediates chromatin remodeling to silence IRF8 expression in non-immune cells in a cell-type specific manner.

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recommendations! Published in 2020 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2020.06.005

Abstract: The regulation of gene expression is a result of a complex interplay between chromatin remodeling, transcription factors (TFs) and signaling molecules. Cell differentiation is accompanied by chromatin remodeling of specific loci to permanently silence genes… read more here.

Keywords: mafk; chromatin remodeling; irf8 expression; expression ... See more keywords
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Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.

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recommendations! Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.06.040

Abstract: Chromosomal rearrangements resulting in the fusion of TMPRSS2, an androgen-regulated gene, and the ETS family transcription factor ERG occur in over half of prostate cancers. However, the mechanism by which ERG promotes oncogenic gene expression… read more here.

Keywords: remodeling complexes; chromatin remodeling; baf; erg ... See more keywords
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Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance.

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recommendations! Published in 2021 at "Trends in molecular medicine"

DOI: 10.1016/j.molmed.2021.04.010

Abstract: Histone eviction and chromatin relaxation are important processes for efficient DNA repair. Poly(ADP) ribose (PAR) polymerase 1 (PARP1) is a key mediator of this process, and disruption of PARP1 activity has a direct impact on… read more here.

Keywords: chromatin remodeling; chromatin; par dependent; studying par ... See more keywords
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Choline ameliorates adult learning deficits and reverses epigenetic modification of chromatin remodeling factors related to adolescent nicotine exposure

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recommendations! Published in 2018 at "Neurobiology of Learning and Memory"

DOI: 10.1016/j.nlm.2018.08.009

Abstract: &NA; Earlier initiation of smoking correlates with higher risk of nicotine dependence, mental health problems, and cognitive impairments. Additionally, exposure to nicotine and/or tobacco smoke during critical developmental periods is associated with lasting epigenetic modifications… read more here.

Keywords: choline; methylation; chromatin remodeling; nicotine exposure ... See more keywords
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Structural transition of the nucleosome during chromatin remodeling and transcription.

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recommendations! Published in 2019 at "Current opinion in structural biology"

DOI: 10.1016/j.sbi.2019.07.011

Abstract: In eukaryotes, the nucleosome is the basic unit of chromatin. Since the genomic DNA is tightly wrapped around the histone octamer in the nucleosome, its function is severely restricted in chromatin. To overcome the nucleosome… read more here.

Keywords: structural transition; remodeling transcription; transition nucleosome; chromatin remodeling ... See more keywords

Chromatin remodeling and retrotransposons activities during regeneration in Drosophila.

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recommendations! Published in 2021 at "Developmental biology"

DOI: 10.1016/j.ydbio.2021.11.005

Abstract: Regeneration is a response mechanism aiming to reconstruct lost or damaged structures. To achieve this, the cells repopulating the lost tissue often have to change their original identity, a process that involves chromatin remodelling.We have… read more here.

Keywords: drosophila; chromatin remodeling; chromatin; retrotransposons activities ... See more keywords

Cell fate conversion: a chromatin remodeling checkpoint revealed

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recommendations! Published in 2017 at "Cell Research"

DOI: 10.1038/cr.2017.44

Abstract: In a new paper in Cell Research, Ji et al. find that transcription factor-instigated opening of chromatin, during cell reprogramming, can be sensed by the Baf60b-containing chromatin remodeling complex, which then activates the ATM-p53 pathway,… read more here.

Keywords: chromatin remodeling; chromatin; conversion; cell fate ... See more keywords