A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.03.012
Abstract: SUMMARY Although the value of proteomics has been demonstrated, cost and scale are typically prohibitive, and gene expression profiling remains dominant for characterizing cellular responses to perturbations. However, high-throughput sentinel assays provide an opportunity for… read more here.
Keywords: characterizing cellular; cellular responses; chromatin signatures; signatures characterizing ... See more keywords
The chromatin signatures of enhancers and their dynamic regulation
Sign Up to like & getrecommendations! Published in 2023 at "Nucleus"
DOI: 10.1080/19491034.2022.2160551
Abstract: ABSTRACT Enhancers are cis-regulatory elements that can stimulate gene expression from distance, and drive precise spatiotemporal gene expression profiles during development. Functional enhancers display specific features including an open chromatin conformation, Histone H3 lysine 27… read more here.
Keywords: dynamic regulation; gene expression; chromatin signatures; chromatin ... See more keywords