Insights into the Establishment of Chromatin States in Pluripotent Cells from Studies of X Inactivation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2017.03.013
Abstract: Animal development entails the sequential and coordinated specialization of cells. During cell differentiation, transcription factors, cell signaling pathways, and chromatin-associated protein complexes cooperate in regulating the expression of a large number of genes. Here, we… read more here.
Keywords: chromatin states; pluripotent cells; states pluripotent; insights establishment ... See more keywords
Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-1005-1
Abstract: Epigenetic modifications play critical roles in modulating gene expression, yet their roles in regulatory networks in human cell lines remain poorly characterized. We integrated multiomics data to construct directed regulatory networks with nodes and edges… read more here.
Keywords: diverse chromatin; chromatin states; cell lines; human cell ... See more keywords
HCVS: Pinpointing Chromatin States Through Hierarchical Clustering and Visualization Scheme
Sign Up to like & getrecommendations! Published in 2019 at "Current Bioinformatics"
DOI: 10.2174/1574893613666180402141107
Abstract: Specific combinations of Histone Modifications (HMs) contributing towards histone code hypothesis lead to various biological functions. HMs combinations have been utilized by various studies to divide the genome into different regions. These study regions have… read more here.
Keywords: chromatin states; hcvs; hierarchical clustering; scheme ... See more keywords
The dynamics of chromatin states mediated by epigenetic modifications during somatic cell reprogramming
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1097780
Abstract: Somatic cell reprogramming (SCR) is the conversion of differentiated somatic cells into totipotent or pluripotent cells through a variety of methods. Somatic cell reprogramming also provides a platform to investigate the role of chromatin-based factors… read more here.
Keywords: chromatin states; somatic cell; epigenetic modifications; totipotency pluripotency ... See more keywords
Characterizing Genetic Regulatory Elements in Ovine Tissues
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.628849
Abstract: The Ovine Functional Annotation of Animal Genomes (FAANG) project, part of the broader livestock species FAANG initiative, aims to identify and characterize gene regulatory elements in domestic sheep. Regulatory element annotation is essential for identifying… read more here.
Keywords: chromatin states; elements ovine; liver spleen; cerebellum ... See more keywords
AppleMDO: A Multi-Dimensional Omics Database for Apple Co-Expression Networks and Chromatin States
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.01333
Abstract: As an economically important crop, apple is one of the most cultivated fruit trees in temperate regions worldwide. Recently, a large number of high-quality transcriptomic and epigenomic datasets for apple were made available to the… read more here.
Keywords: chromatin states; expression networks; database; apple ... See more keywords
DNA Sequence-Dependent Properties of Nucleosome Positioning in Regions of Distinct Chromatin States in Mouse Embryonic Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214488
Abstract: Chromatin architecture is orchestrated, and plays crucial roles during the developmental process by regulating gene expression. In embryonic stem cells (ESCs), three types of chromatin states, including active, repressive and poised states, were previously identified… read more here.
Keywords: chromatin states; sequence dependent; model; chromatin ... See more keywords