Ecofriendly appraisal of stability-indicating high-performance chromatographic assay of canagliflozin and metformin with their toxic impurities; in silico toxicity prediction.
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DOI: 10.1002/jssc.202200754
Abstract: Canagliflozin is an oral hypoglycemic drug recently formulated in combination with a biguanide, metformin hydrochloride, for improving its hypoglycemic action. Canagliflozin has one reported major degradation product, also metformin hydrochloride has one reported major degradation… read more here.
Keywords: canagliflozin metformin; toxicity; toxic; chromatographic assay ... See more keywords