A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23485
Abstract: Acalabrutinib is aided in the treatment of various cancers, which acts by inhibiting Bruton tyrosine kinase. Acalabrutinib belongs to the imidazopyrazine class consisting of a chiral carbon, resulting in two enantiomers. Currently, no methods exist… read more here.
Keywords: validated chiral; acalabrutinib; chromatographic method; chiral chromatographic ... See more keywords
Validated ecofriendly chromatographic method for quantitative determination of anti migraine quaternary mixture.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000256
Abstract: A novel ecofriendly, cost and time saving high performance thin layer chromatographic method was developed and validated for simultaneous determination of metoclopramide, ergotamine, caffeine and paracetamol in bulk and pharmaceutical formulation. The separation was carried… read more here.
Keywords: method quantitative; determination; method; validated ecofriendly ... See more keywords
Cost-effective green chromatographic method for the simultaneous determination of four commonly used direct-acting antiviral drugs in plasma and various pharmaceutical formulations
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106512
Abstract: Abstract This article presents the simultaneous determination of multiple recently approved direct-acting antiviral (DAA) regimens using a sensitive, robust method. Reversed-phase high-performance liquid chromatographic method (RP-HPLC) has been developed to represent a green alternative of… read more here.
Keywords: simultaneous determination; method; direct acting; acting antiviral ... See more keywords
Chromatographic method for the determination of inflammatory biomarkers and uric acid in human saliva.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122598
Abstract: Determination of concentration of biomarkers of the activation of immune system, uric acid, and creatinine in the saliva can be useful tool for the diagnosis and monitoring of early manifestations of diseases such as malignant,… read more here.
Keywords: uric acid; determination; human saliva; method ... See more keywords
Green Chromatographic Method for Determination of Active Pharmaceutical Ingredient, Preservative, and Antioxidant in an Injectable Formulation: Robustness by Design Expert
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DOI: 10.1021/acsomega.2c03387
Abstract: We report an efficient HPLC method for simultaneous qualitative and quantitative analysis of lincosamide antibiotic injectable formulations containing Clindamycin phosphate (CMN), benzyl alcohol (BA), and ethylenediaminetetraacetic acid (EDTA) as major ingredients. The three components were… read more here.
Keywords: green chromatographic; method determination; design; robustness ... See more keywords
Development of a Novel Thin-Layer Chromatographic Method of Screening the Red Beet (Beta vulgaris L.) Pigments in Alimentary Products.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmz099
Abstract: The aim of this study was to develop a thin-layer chromatographic method of qualitative analysis, aiming to confirm the presence of the red beetroot pigments in a given sample. The TLC system developed for this… read more here.
Keywords: chromatographic method; development novel; layer chromatographic; thin layer ... See more keywords
A Validated Liquid Chromatographic Method for Berberine Analysis in Tissue and Application
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Analytical Chemistry"
DOI: 10.1155/2020/8892696
Abstract: Simple and rapid high-performance liquid chromatography methods were developed for the determination of berberine (BB) in various rat tissues so as to evaluate a P-gp inhibitor, glycyrrhetinic acid (GA), on BB's oral bioavailability. Acetonitrile was… read more here.
Keywords: validated liquid; tissue; method berberine; chromatographic method ... See more keywords
CHROMATOGRAPHIC METHOD FOR THE ANALYSIS OF SOME PHARMACEUTICAL COMPOUNDS FROM RIVER WATER
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Engineering and Management Journal"
DOI: 10.30638/eemj.2017.008
Abstract: The pharmaceutical compounds are emerging pollutants for which the international scientific community has paid special attention in recent years, because these substances can have adverse effects on living organisms in the aquatic environment. In this… read more here.
Keywords: water; pharmaceutical compounds; method; river water ... See more keywords
Optimization and Validation of a Chromatographic Method for the Quantification of Isoniazid in Urine of Tuberculosis Patients According to the European Medicines Agency Guideline
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DOI: 10.3390/antibiotics7040107
Abstract: Isoniazid is a drug that is widely used against tuberculosis. However, it shows high interpatient variability in metabolism kinetics and clinical effect, which complicates the prescription of the medication and jeopardizes the success of the… read more here.
Keywords: european medicines; isoniazid urine; method; medicines agency ... See more keywords
New Stability indicating ultrafast liquid chromatographic method for the determination of Teicoplanin in injection
Sign Up to like & getrecommendations! Published in 2018 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2018.00827.2
Abstract: Teicoplanin is an antibiotic belonging to glycopeptides. A selective, specific and sensitive stability-indicating high-performance liquid chromatographic method was developed and validated for the determination of Teicoplanin in tablet dosage forms. Reversed-phase chromatography was performed on… read more here.
Keywords: determination teicoplanin; chromatographic method; stability indicating; method ... See more keywords