In vitro metabolism of the novel synthetic opioid agonist cyclopropylfentanyl and subsequent confirmation in authentic human samples using liquid chromatography-high resolution mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2611
Abstract: Novel synthetic opioids (NSOs) are a class of novel psychoactive substances (NPS) that are growing in popularity and presenting a significant public health risk. Included in this class are derivatives of the highly potent analgesic,… read more here.
Keywords: high resolution; chromatography high; novel synthetic; mass ... See more keywords
Identification of glycated sites in ovalbumin under freeze-drying processing by liquid chromatography high-resolution mass spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.01.038
Abstract: The glycation reaction between ovalbumin and d-glucose during freeze-drying was investigated and the mechanism of protection of the protein structure was studied, the precise glycated sites and degree of substitution per peptide (DSP) of each… read more here.
Keywords: high resolution; freeze drying; chromatography high; glycated sites ... See more keywords
High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS)
Sign Up to like & getrecommendations! Published in 2017 at "Microchemical Journal"
DOI: 10.1016/j.microc.2017.03.050
Abstract: Abstract A liquid chromatography–high resolution mass spectrometry (LC-HRMS) method for the simultaneous screening in hair samples of drugs of abuse and medicaments was developed. Target analytes screened using a single extraction and analytical run were… read more here.
Keywords: high resolution; chromatography high; mass; drugs abuse ... See more keywords
MetEx: A Targeted Extraction Strategy for Improving the Coverage and Accuracy of Metabolite Annotation in Liquid Chromatography-High-Resolution Mass Spectrometry Data.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04783
Abstract: Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) is the most popular platform for untargeted metabolomics studies, but compound annotation is a challenge. In this work, we developed a new LC-HRMS data-targeted extraction method called MetEx for metabolite… read more here.
Keywords: liquid chromatography; mass spectrometry; resolution mass; high resolution ... See more keywords
Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography-High-Resolution Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00253
Abstract: The surge in electronic cigarette (e-cig) use in recent years has raised questions on chemical exposures that may result from vaping. Previous studies have focused on measuring known toxicants, particularly those present in traditional cigarettes,… read more here.
Keywords: high resolution; chromatography high; mass; liquid chromatography ... See more keywords
Nontarget Analysis of Oxygenates in Catalytic Fast Pyrolysis Biocrudes by Supercritical Fluid Chromatography High-Resolution Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Energy & Fuels"
DOI: 10.1021/acs.energyfuels.8b02983
Abstract: Catalytic fast pyrolysis (CFP) biocrudes can comprise up to 30 wt % of oxygen content in compounds such as polyphenols, acids, carbonyls, and anhydrosugars and thus require upgrading by, e.g., hydrotreatment, to produce transport fuels.… read more here.
Keywords: chromatography high; fast pyrolysis; analysis; catalytic fast ... See more keywords
Discovery of Spoilage Markers for Chicken Eggs Using Liquid Chromatography-High Resolution Mass Spectrometry-Based Untargeted and Targeted Foodomics.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c01009
Abstract: The current approaches remain insufficient for measuring chicken egg spoilage or present analytical limitations. This study aimed to complement the existing analyses and identify novel markers using liquid chromatography-high resolution mass spectrometry-based foodomics strategies. In… read more here.
Keywords: spoilage; high resolution; chromatography high; chicken eggs ... See more keywords
Determination of Pesticides in Organic Carrots by High-Performance Liquid Chromatography/High-Resolution Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Letters"
DOI: 10.1080/00032719.2018.1434664
Abstract: ABSTRACT Food contamination by pesticide residues, which may cause serious human health problems, is an ongoing challenge. Safer organically grown food is therefore needed. However, best practices are not always followed for farming organic foods,… read more here.
Keywords: high resolution; chromatography high; organic foods; liquid chromatography ... See more keywords
Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) analysis following voluntary carvedilol poisoning in a subject with cirrhosis: a case report.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac078
Abstract: Accidental or intentional carvedilol poisoning is rarely reported. Here, we describe a case of attempted suicide with a large quantity of immediate-release carvedilol (75 mg) and alcohol. In order to determine the kinetics, LC-HRMS analyses… read more here.
Keywords: liquid chromatography; hours ingestion; carvedilol poisoning; case ... See more keywords
Lipidomics Analysis of Free Fatty Acids in Human Plasma of Healthy and Diabetic Subjects by Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS)
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051189
Abstract: Targeted analytical methods for the determination of free fatty acids (FFAs) in human plasma are of high interest because they may help in identifying biomarkers for diseases and in monitoring the progress of a disease.… read more here.
Keywords: human plasma; liquid chromatography; free fatty; high resolution ... See more keywords
Identification of Degradation Products of the New Anticancer Drug Substance ONC201 by Liquid Chromatography–High-Resolution Multistage Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2023 at "Chemosensors"
DOI: 10.3390/chemosensors11050294
Abstract: ONC201 (dordaviprone) is a new drug substance used in a compassionate manner to treat patients with glioblastoma. Given the clinical context and the particularly promising preclinical results, we have been asked by the medical authorities… read more here.
Keywords: liquid chromatography; high resolution; drug substance; chromatography high ... See more keywords