Development of a high-performance liquid chromatography method for the simultaneous determination of chiral impurities and assay of (S)-clopidogrel using a cellulose-based chiral stationary phase in methanol/water mode.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of separation science"
DOI: 10.1002/jssc.201701191
Abstract: A simple reversed-phase high-performance liquid chromatography method for the chiral separation of the active pharmaceutical ingredient (S)-clopidogrel has been developed on the cellulose-based Chiralcel OJ-RH chiral stationary phase. The S enantiomer was baseline resolved from… read more here.
Keywords: phase; method; liquid chromatography; chromatography method ... See more keywords
Development of a gel permeation chromatography method for analysing cellulose nitrate in museums.
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DOI: 10.1002/jssc.202001018
Abstract: This paper describes the development of a suitable Gel Permeation Chromatography method for cellulose nitrate plasticised with camphor (celluloid) found in cultural heritage. Current sample preparation and dissolution methods, apart from focusing on native, non-derivatised… read more here.
Keywords: permeation chromatography; method; cellulose nitrate; chromatography method ... See more keywords
Implementation of QRM and DoE-Based Quality by Design Approach to VEER Chromatography Method for Simultaneous Estimation of Multiple Combined Dosage Forms of Paracetamol
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DOI: 10.1007/s12247-020-09490-w
Abstract: Paracetamol is a well-known OTC drug, and several combinations are available in the market. The numbers of chromatography methods were published for analysis of combined pharmaceutical dosage form of paracetamol. But every combination needs separate… read more here.
Keywords: method; combined dosage; chromatography method; dosage ... See more keywords
Development and validation of a liquid chromatography‐MS/MS method for simultaneous quantification of tenofovir and efavirenz in biological tissues and fluids
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2016.12.028
Abstract: &NA; Millions of people worldwide live with human immunodeficiency virus (HIV) infection thus justifying the continuous search for new prevention and treatment strategies, including topical microbicide products combining antiretroviral drugs (ARVs) such as tenofovir (TFV)… read more here.
Keywords: tissues fluids; tenofovir; method; tfv ... See more keywords
A generic gas chromatography method for determination of residual solvents in PET radiopharmaceuticals.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114425
Abstract: A novel gas chromatography (GC) method for quantitation of volatile organic compounds (VOCs) in 18F- and 11C-radiopharmaceuticals listed in the European Pharmacopoeia (Ph. Eur.) was proposed. Optimized chromatographic parameters were used for separation of ethanol,… read more here.
Keywords: gas chromatography; pet radiopharmaceuticals; residual solvents; method ... See more keywords