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Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200459
Abstract: A series of 1H‐1,2,3‐triazole−4H‐chromene−D‐glucose hybrid compounds 7a–w were synthesized using click chemistry of 2‐amino‐7‐propargyloxy‐4H‐chromene‐3‐carbonitriles 5a–w. CuNPs@montmorillonite was used as a catalyst in the presence of DIPEA as an additive for this chemistry. All synthesized 1H‐1,2,3‐triazoles…
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Keywords:
chemistry;
chromene;
glucose hybrid;
protein ... See more keywords
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Published in 2017 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-017-2085-x
Abstract: A novel series of spiro[chromene-2,1'-cyclohexan]-4(3H)-one derivatives containing either a chalcone or flavanone fragment in their molecules was synthesized. 2'-Hydroxychalcones, containing a spirochromanone moiety, underwent cyclocondensation with formation of a condensed pyran ring. The catalytic efficiency…
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Keywords:
route synthesis;
chromene;
synthesis functionalized;
efficient route ... See more keywords
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Published in 2019 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-019-01295-w
Abstract: The present work encompasses development of a new class of active antimicrobial agents of the ɳ 6 -arene-ɳ 5 -cyclopentadienyliron (II) complexes and polymers to expand the existing family of antimicrobials. The design of the…
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Keywords:
complexes polymers;
chromene;
first example;
cyclopentadienyliron ... See more keywords
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Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105475
Abstract: An array of 4-aryl-2-amino-4H chromene derivatives were designed, synthesized, and evaluated for cytotoxic activity against four cancer cell lines and two non-cancerous cell lines. The most active candidates were further screened for their in vitro…
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Keywords:
chromene;
cell lines;
cancer cell;
cancer ... See more keywords
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Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.01.060
Abstract: The series of 2-amino-7-propargyloxy-4H-chromene-3-carbonitriles 5a-t were synthesized from corresponding 2-amino-7-phydroxy-4H-chromene-3-carbonitriles 4a-t and propargyl bromide. Two procedures were used in these syntheses: K2CO3/acetone and NaH/DMF procedures with yields of 65-89% and 80-96%, respectively. 1H-1,2,3-Triazole-tethered 4H-chromene-d-glucose conjugates…
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Keywords:
chromene;
chromene glucose;
chemistry;
tethered chromene ... See more keywords
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Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131183
Abstract: Abstract An efficient, environmentally friendly, one-pot three-component synthesis of a series of 2H-chromene-based imidazo[1,2-a]pyridines had been designed and were synthesized. This protocol was developed by the reaction of substituted 2H-chromene aldehydes and 2-aminopyridine in a…
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Keywords:
peptide deformylase;
based imidazo;
molecular docking;
one pot ... See more keywords
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Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.06.012
Abstract: Abstract New 4-oxo-2-vinyl-4H-chromene-3-carbonitrile derivatives have been synthesized by the Knoevenagel reaction of 2-methyl-4-oxo-4H-chromene-3-carbonitrile with aromatic and heteroaromatic aldehydes. Spectral properties of the obtained compounds have been studied.
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Keywords:
chromene carbonitrile;
chromene;
oxo vinyl;
knoevenagel reaction ... See more keywords
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Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02798
Abstract: A novel hybrid bisphotochromic system involving a chromene residue and a styryl dye fragment is described. Initially, the compound shows almost no photochromism due to intramolecular energy and electron transfer between the chromophores. Protonation of…
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Keywords:
styryl;
chromene;
styryl dye;
protonation ... See more keywords
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Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b02467
Abstract: A one-pot greener methodology has been adopted for the synthesis of a simple 4H-chromene core-based fluorescent tag of (S)-2-amino-4-(anthracen-9-yl)-7-hydroxy-4H-chromene-3-carbonitrile (AHC), and its structure has been analyzed using NMR spectroscopy. The physicochemical properties of AHC were…
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Keywords:
hydroxy chromene;
chromene;
anthracen hydroxy;
amino anthracen ... See more keywords
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Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c8nj04938f
Abstract: A new magnetic nano-catalyst bearing ionic liquid, ferrocene and BiOCl was synthesized and its catalytic activities were evaluated in the synthesis of a wide variety of 2-amino-3-cyano-4H-chromene derivatives (54 compounds) under ultrasound irradiation.
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Keywords:
biocl;
synthesis characterization;
synthesis;
characterization novel ... See more keywords
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Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra07809f
Abstract: One-pot synthesis of C2-symmetric chromene derivatives, which serve as building blocks to prepare liquid crystals with potential electrical or optical properties.
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Keywords:
methodology;
rapid catalyst;
chromene;
chromene derivatives ... See more keywords