Formal [3+3] Cyclization Between 3‐Alkynyl‐3‐hydroxyisoindolinones and Substituted Phenols to 2 H ‐Chromene Based Spiro ‐isoindolinones
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.70260
Abstract: We herein reported a formal [3+3] cyclization reaction between 3‐alkynyl‐3‐hydroxyisoindolinones and substituted phenols, which offered an efficient procedure for the preparation of 2 H ‐chromene‐based spiro ‐isoindolinones. 10 mol% of inexpensive catalyst (Cu(ClO 4 )… read more here.
Keywords: substituted phenols; formal cyclization; hydroxyisoindolinones substituted; chromene based ... See more keywords
Design, one-pot synthesis, molecular docking study, and antibacterial evaluation of novel 2H-chromene based imidazo[1,2-a]pyridine derivatives as potent peptide deformylase inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131183
Abstract: Abstract An efficient, environmentally friendly, one-pot three-component synthesis of a series of 2H-chromene-based imidazo[1,2-a]pyridines had been designed and were synthesized. This protocol was developed by the reaction of substituted 2H-chromene aldehydes and 2-aminopyridine in a… read more here.
Keywords: peptide deformylase; based imidazo; molecular docking; one pot ... See more keywords